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CAS No 596-51-0 , Glycopyrrolate

  • Name: Glycopyrrolate
  • Synonyms: Glycopyrrolate;(1,1-Dimethyl-2,3,4,5-tetrahydropyrrol-3-yl) 2-cyclopentyl-2-hydroxy-2-phenyl-acetate bromide; Glycopyrronium bromide;
  • CAS Registry Number:
  • Melting Point: 193 - 194.5
  • EINECS: 209-887-0
  • Molecular Weight: 398.34
  • InChI: InChI=1/C20H30NO3.BrH/c1-21(2)13-12-18(15-21)24-19(22)14-20(23,17-10-6-7-11-17)16-8-4-3-5-9-16;/h3-5,8-9,17-18,23H,6-7,10-15H2,1-2H3;1H/q+1;/p-1
  • Molecular Formula: C19H28NO3.Br
  • Molecular Structure:CAS No:596-51-0 Glycopyrrolate

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596-51-0 Glycopyrrolate

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References of Glycopyrrolate
Title: Glycopyrrolate
CAS Registry Number: 596-51-0
CAS Name: 3-[(Cyclopentylhydroxyphenylacetyl)oxy]-1,1-dimethylpyrrolidinium bromide
Synonyms: 3-hydroxy-1,1-dimethylpyrrolidinium bromide a-cyclopentylmandelate; a-cyclopentylmandelic acid ester with 3-hydroxy-1,1-dimethylpyrrolidinium bromide; 1-methyl-3-pyrrolidyl a-cyclopentylmandelate methobromide; 1-methyl-3-pyrrolidyl a-phenyl-a-cyclopentylglycolate methobromide; 3-(2-phenyl-2-cyclopentylglycoloyloxy)-1,1-dimethylpyrrolidinium bromide; glycopyrronium bromide
Manufacturers' Codes: AHR-504
Trademarks: Nodapton; Robanul; Robinul (Robins); Tarodyl; Tarodyn
Molecular Formula: C19H28BrNO3
Molecular Weight: 398.33
Percent Composition: C 57.29%, H 7.09%, Br 20.06%, N 3.52%, O 12.05%
Literature References: Synthetic, quaternary ammonium anticholinergic. Prepn: Franko, Lunsford, J. Med. Pharm. Chem. 2, 523 (1960); Lunsford, US 2956062 (1960 to A. H. Robins). Pharmacodynamics: E. Kaltiala et al., J. Pharm. Pharmacol. 26, 352 (1974). Toxicology: B. V. Franko et al., Toxicol. Appl. Pharmacol. 17, 361 (1970). Clinical comparison with atropine in anaesthetic practice: F. Kongsrud, S. Sponheim, Acta Anaesthesiol. Scand. 26, 620 (1982); A. I. Webb, R. M. McMurphy, Am. J. Vet. Res. 48, 1733 (1987); B. V. G. Malling et al., Br. J. Anaesth. 60, 426 (1988). Brief review of pharmacology and clinical use: R. K. Mirakhur, J. W. Dundee, Anaesthesia 38, 1195-1204 (1983).
Properties: White crystals from butanone, mp 193.2-194.5°. Sol in water. LD50 (72 hr.) in female mice, female rats (mg/kg): 107, 196 i.p.; in male rats (mg/kg): 1150 orally (Franko).
Melting point: mp 193.2-194.5°
Toxicity data: LD50 (72 hr.) in female mice, female rats (mg/kg): 107, 196 i.p.; in male rats (mg/kg): 1150 orally (Franko)
Therap-Cat: Antispasmodic; preanesthetic medicant.
Therap-Cat-Vet: Preanesthetic medicant.
Keywords: Antimuscarinic; Antispasmodic.