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CAS No 59227-89-3 , 1-dodecylazepan-2-one

  • Name: 1-dodecylazepan-2-one
  • Synonyms: Tranzone; 59227-89-3; N-Dodecylcaprolactam; 1-dodecylazepan-2-one;Azone;1-dodecylazepan-2-one; N-Lauryl caprolactam; 1-Dodecylazacycloheptan-2-one;
  • CAS Registry Number:
  • Melting Point: -7 deg C
  • Boiling Point: 350
  • Density: 0.906-0.926
  • Refractive index: 1.470-1.473
  • Water Solubility: Insoluble in water, and form emulsions with water, soluble in various organic solvents.
  • EINECS: 261-668-9
  • Molecular Weight: 281.4766
  • InchiKey: AXTGDCSMTYGJND-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-13-16-19-17-14-11-12-15-18(19)
    20/h2-17H2,1H3
  • Molecular Formula: C18H35NO
  • Molecular Structure:CAS No:59227-89-3 1-dodecylazepan-2-one
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59227-89-3 Laurocapram

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59227-89-3 Laurocapram

  • China Anhui Jinao Chemical Co.,Ltd. [Manufacturers]
  • Tel: +86-551-342 0438
  • Fax: +86-551-342 3438
  • Address: Ma'anshan Nanlu, Baohe district, Hefei, Anhui, China Hefei,AnhuiChina
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59227-89-3 Laurocapram

  • China Beijing Brilliance Biochemical Co., Ltd. [Manufacturers]
  • Tel: +86-(10)-8776-6923-ex-19
  • Fax: +86-(10)-8774-8771
  • Address: Yongle Economic Development Area, Tongzhou, Beijing, Beijing, Beijing,BeijingChina
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59227-89-3 Laurocapram

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59227-89-3 Laurocapram

  • China Liangyungang Jiewei Chemical Co., Ltd. [Manufacturers]
  • Tel: 0086-518-85639881 013505133131
  • Fax: 0086-518-85633529
  • Address: Xilin Road,Shenwei,Xinpu,Lianyungang City,China Lianyungang,jiangsuChina
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59227-89-3 LAUROCAPRAM

  • LAUROCAPRAMAZONE, 99%
  • China Chengdu Kedong Chemical Company Ltd [Manufacturer]
  • Tel: +86-28-85919158
  • Fax: +86-28-85913778
  • Address: No.9 Block 4 Renmin Nan Road , Chengdu,PRC 610041 Chengdu CHINA Chengdu,nullChina
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59227-89-3 Laurocapram

  • LaurocapramAzone, 95-99%
  • China Zhengzhou Nongda Biochemical Products Plant [Manufacturers]
  • Tel: 0086-371-60151011 60151033 13503818945
  • Fax: +86-371-60151077
  • Address: 27/F, Xinmangguo mansion, CBD, Zhengdong new district, Zhengzhou, China 俄国犯嘀咕,多福多寿China
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59227-89-3 Azone

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59227-89-3 AZOTE KETONE 95%

  • AZOTE KETONE 95%
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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59227-89-3 Laurocapram

  • Laurocapram
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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References of 1-dodecylazepan-2-one
Title: Laurocapram
CAS Registry Number: 59227-89-3
CAS Name: 1-Dodecylhexahydro-2H-azepin-2-one
Synonyms: 1-dodecylazacycloheptan-2-one; N-dodecyl-e-caprolactam
Manufacturers' Codes: N-0252
Trademarks: Azone (Nelson)
Molecular Formula: C18H35NO
Molecular Weight: 281.48
Percent Composition: C 76.81%, H 12.53%, N 4.98%, O 5.68%
Literature References: Caprolactam derivative used to enhance percutaneous absorption of physiologically active agents. Also exhibits intrinsic anti-inflammatory activity. Prepn: A. P. Swain et al., J. Org. Chem. 18, 1087 (1953). Improved synthesis: V. J. Rajadhyaksha et al., EP 95096; eidem, US 4422970 (both 1983 to Nelson). Use as skin penetrant: V. J. Rajadhyaksha, US 3989816; US 4405616 (1976, 1983 to Nelson). Anti-inflammatory activity: E. L. Nelson, US 4310525 (1982 to Nelson). Pharmacology: R. B. Stoughton, Arch. Dermatol. 118, 474 (1982). Comprehensive description: idem, Drug Dev. Ind. Pharm. 9, 725 (1983). Topical antiviral activity in vivo: M. F. Leonard et al., Chemotherapy (Basel) 33, 151 (1987).
Properties: Clear, colorless liquid, mp -7°. bp50m 160°. d 0.91; n 1.4701. Insol in water. Freely sol in most organic solvents. LD50 rats, mice (g/kg): 8 i.v., i.p. (Stoughton).
Melting point: mp -7°
Boiling point: bp50m 160°
Index of refraction: n 1.4701
Density: d 0.91
Toxicity data: LD50 rats, mice (g/kg): 8 i.v., i.p. (Stoughton)
Use: Pharmaceutic aid (excipient).