Title: N-Nitrosomorpholine
CAS Registry Number: 59-89-2
CAS Name: 4-Nitrosomorpholine
Synonyms: NMOR
Molecular Formula: C4H8N2O2
Molecular Weight: 116.12
Percent Composition: C 41.37%, H 6.94%, N 24.12%, O 27.56%
Literature References: Prepn: L. Knorr,
Ann. 301, 1 (1898); F. Chapman,
J. Chem. Soc. 1949, 1631; G. Oláh
et al., Ber. 89, 2374 (1956). Metabolism: B. W. Stewart, P. N. Magee,
Biochem. J. 126, 21P (1972). Carcinogenicity studies: H. Druckrey
et al., Naturwissenschaften 48, 134 (1961); P. Bannasch, H.-A. Müller,
Arzneim.-Forsch. 14, 805 (1964);
IARC Monographs 17, 263 (1978).
Properties: Yellow crystals, mp 29°. bp25 139-140°; bp747 224-224.5°. Sol in water. LD50 orally in rats: 282 mg/kg (Druckrey).
Melting point: mp 29°
Boiling point: bp25 139-140°; bp747 224-224.5°
Toxicity data: LD50 orally in rats: 282 mg/kg (Druckrey)
CAUTION: This substance is reasonably anticipated to be a human carcinogen:
Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-205.