Home > Name List By 9 > 9-chloro-7-(2H-tetrazol-5-yl)chromeno[2,3-b]pyridin-5-one

CAS No 58712-69-9 , 9-chloro-7-(2H-tetrazol-5-yl)chromeno[2,3-b]pyridin-5-one

  • Name: 9-chloro-7-(2H-tetrazol-5-yl)chromeno[2,3-b]pyridin-5-one
  • Synonyms: 9-chloro-7-(1H-tetrazol-5-yl)-;Traxanoxum [INN-Latin];9-chloro-7-(2H-tetrazol-5-yl)chromeno[2,3-b]pyridin-5-one; 5H-(1)Benzopyrano(2,3-b)pyridin-5-one;
  • CAS Registry Number:
  • Flash Point: 321.2°C
  • Boiling Point: 607.5°Cat760mmHg
  • Density: 1.645g/cm3
  • Refractive index: 1.718
  • Flash Point: 321.2°C
  • Molecular Weight: 299.67204
  • InchiKey: MLCGWPUVZKTVLO-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H6ClN5O2/c14-9-5-6(12-16-18-19-17-12)4-8-10(20)7-2-1-3-15-13
    (7)21-11(8)9/h1-5H,(H,16,17,18,19)
  • Molecular Formula: C13H6ClN5O2
  • Molecular Structure:CAS No:58712-69-9 9-chloro-7-(2H-tetrazol-5-yl)chromeno[2,3-b]pyridin-5-one

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58712-69-9 TRAXANOX

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References of 9-chloro-7-(2H-tetrazol-5-yl)chromeno[2,3-b]pyridin-5-one
Title: Traxanox
CAS Registry Number: 58712-69-9
CAS Name: 9-Chloro-7-(1H-tetrazol-5-yl)-5H-[1]benzopyrano[2,3-b]pyridin-5-one
Synonyms: 9-chloro-7-(5-1H-tetrazolyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine
Molecular Formula: C13H6ClN5O2
Molecular Weight: 299.67
Percent Composition: C 52.10%, H 2.02%, Cl 11.83%, N 23.37%, O 10.68%
Literature References: Antiallergic agent which selectively inhibits release of allergic mediators from mast cells. Prepn: T. Oe, M. Tsuruda, DE 2521980; eidem, US 4085111 (1975, 1978 both to Yoshitomi). Antianaphylactic activity in animals: K. Goto et al., Jpn. J. Pharmacol. 30, 537 (1980). Mechanism of action study: K. Goto et al., Int. Arch. Allergy Appl. Immunol. 68, 332 (1982). Clinical pharmacology and pharmacokinetics: A. Ebihara et al., Arzneim.-Forsch. 37, 1388 (1987). Metabolism in humans: M. Tateno et al., Yakuri to Chiryo 16, 3251 (1988), C.A. 110, 18040n (1989).
Properties: mp >300°.
Melting point: mp >300°
 
Derivative Type: Sodium salt pentahydrate
Manufacturers' Codes: Y-12141
Trademarks: Clearnal (Yoshitomi)
Molecular Formula: C13H5ClN5NaO2.5H2O
Molecular Weight: 411.73
Percent Composition: C 37.92%, H 3.67%, Cl 8.61%, N 17.01%, Na 5.58%, O 27.20%
 
Therap-Cat: Antiallergic; antiasthmatic.
Keywords: Antiallergic; Antiasthmatic (Nonbronchodilator).