CAS No 5868-06-4 , 8-Azoniabicyclo[3.2.1]octane,8-(2-[1,1'-biphenyl]-4-yl-2-oxoethyl)-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-,bromide, (3-endo,8-anti)- (9CI)

Name: 8-Azoniabicyclo[3.2.1]octane,8-(2-[1,1'-biphenyl]-4-yl-2-oxoethyl)-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-,bromide, (3-endo,8-anti)- (9CI)
Synonyms: 8-(p-Phenylphenacyl)hyoscyaminium bromide (7CI); N-(4-Phenylphenacyl)-l-hyoscyaminiumbromide; Fa 402; FentoniumBromide; Phentonium bromide; Ketoscillium;1aH,5aH-Tropanium, 3a-hydroxy-8-(p-phenylphenacyl)-, bromide, (-)-tropate(8CI); Tropic acid, (-)-, ester with 3a-hydroxy-8-(p-phenylphenacyl)-1aH,5aH-tropanium bromide (8CI); Z 326; Phentonium; Phenthonium; Phenthoniumbromide; N-(4'-Phenylphenacyl)hyoscyaminium bromide;8-Azoniabicyclo[3.2.1]octane,8-(2-[1,1'-biphenyl]-4-yl-2-oxoethyl)-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-,bromide, (3-endo,8-anti)- (9CI); Ketoscilium;anti-N-(4-Phenylphenacyl)-l-hyoscyamine bromide; 3a-Hydroxy-8-(p-phenylphenacyl)-1aH,5aH-tropanium bromide (-)-tropate;8-Azoniabicyclo[3.2.1]octane,8-(2-[1,1'-biphenyl]-4-yl-2-oxoethyl)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-,bromide, [3(S)-endo,anti]-; Ulcesium;
CAS Registry Number:5868-06-4
Flash Point: °C
Boiling Point: °Cat760mmHg
Density: g/cm³
Flash Point: °C
EINECS: 227-520-2
Molecular Weight: 0
InChI: InChI=1/C31H34NO4.BrH/c1-32(20-30(34)25-14-12-23(13-15-25)22-8-4-2-5-9-22)26-16-17-27(32)19-28(18-26)36-31(35)29(21-33)24-10-6-3-7-11-24;/h2-15,26-29,33H,16-21H2,1H3;1H/q+1;/p-1
Molecular Formula: C31H34 N O4 . Br
Molecular Structure:

Related products

Select to

5868-06-4 Fentonium Bromide

Fentonium Bromide, 99%
Facus Pharmaceutical Co., Ltd. [Manufacturer]
Tel: +86-(0)574-62378411
Fax: +86-(0)574-62378410
Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina

5868-06-4 FENTONIUM BROMIDE

Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
Fax: +86 25 8345-3275
Address: Rm.902 Longyin Plaza,
No. 217 Zhongshan Rd.
(N)Nanjing 210009,China null,nullChina

Select to

1/1

References of 8-Azoniabicyclo[3.2.1]octane,8-(2-[1,1'-biphenyl]-4-yl-2-oxoethyl)-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-,bromide, (3-endo,8-anti)- (9CI)

Title: Fentonium Bromide
CAS Registry Number: 5868-06-4
CAS Name: [3(S)-endo]-8-(2-[1,1￠-Biphenyl]-4-yl-2-oxoethyl)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
Synonyms: 3a-hydroxy-8-(p-phenylphenacyl)-1aH,5aH-tropanium bromide (-)-tropate; N-(4-phenylphenacyl)-1-hyoscyaminium bromide; phentonium bromide
Manufacturers' Codes: FA-402; Z-326
Trademarks: Ketoscilium (Zambon); Ulcesium (Zambon)
Molecular Formula: C31H34BrNO4
Molecular Weight: 564.51
Percent Composition: C 65.96%, H 6.07%, Br 14.15%, N 2.48%, O 11.34%
Literature References: Anticholinergic. Prepn: U. Teotino, D. Della Bella, GB 1026640; eidem, US 3356682 (1966, 1967 both to Whitefin Holding); Teotino et al., Chim. Ther. 3, 453 (1968). Human pharmacology: Azzollini et al., Curr. Ther. Res. 12, 734 (1970). Clinical studies: Alberto et al., Minerva Med. 62, 852 (1971).
Properties: Crystals, mp 203-205° (dec). [a]D23 -5.68° (c = 5 in DMF). Also reported as mp 193-194°. [a]D25 -4.7° (c = 5 in DMF). LD50 in mice (mg/kg): 12.1 i.v.; >400 s.c. and orally (Teotino, Della Bella).
Melting point: mp 203-205° (dec); mp 193-194°
Optical Rotation: [a]D23 -5.68° (c = 5 in DMF); [a]D25 -4.7° (c = 5 in DMF)
Toxicity data: LD50 in mice (mg/kg): 12.1 i.v.; >400 s.c. and orally (Teotino, Della Bella)
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic; Antimuscarinic.