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CAS No 58-34-4 , methyl sulfate

  • Name: methyl sulfate
  • Synonyms: Multezin; Thiazinamium methyl sulfate;Multergan; Padisal;trimethyl(1-phenothiazin-10-ylpropan-2-yl)azanium; Prothazin methosulfate; Valan;methyl sulfate; Thiazinamium metilsulfate;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Safety Statements: Poison by ingestion and intraperitoneal routes. An antihistamine and anticholinergic agent. When heated to decomposition it emits very toxic fumes of SOx, NH3, and NOx.
  • Flash Point: °C
  • EINECS: 200-376-8
  • Molecular Weight: 410.55074
  • InchiKey: BVIDQAVCCRUFGU-UHFFFAOYSA-M
  • InChI: InChI=1S/C18H23N2S.CH4O4S/c1-14(20(2,
    3)4)13-19-15-9-5-7-11-17(15)21-18-12-8-6-10-16(18)19;1-5-6(2,3)4/h5-12,
    14H,13H2,1-4H3;1H3,(H,2,3,4)/q+1;/p-1
  • Molecular Formula: C19H26N2O4S2
  • Molecular Structure:CAS No:58-34-4 methyl sulfate
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58-34-4 THIAZINAMIUM METILSULFATE

  • United States 2A PharmaChem USA [Manufacturer]
  • Tel: 630-322-8887
  • Fax: 630-322-8885
  • Address: 2A PharmaChem USA
    5403 Patton Drive, Suite 208
    Lisle, Illinois 60532 null,nullUnited States
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58-34-4 THIAZINAMIUM METILSULFATE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of methyl sulfate
Title: Thiazinamium Methylsulfate
CAS Registry Number: 58-34-4
CAS Name: N,N,N,a-Tetramethyl-10H-phenothiazine-10-ethanaminium methyl sulfate
Synonyms: trimethyl(1-methyl-2-phenothiazin-10-ylethyl)ammonium methyl sulfate; trimethyl[1-methyl-2-(10-phenothiazinyl)ethyl]ammonium methyl sulfate; N-[b-(10-phenothiazinyl)propyl]trimethylammonium methyl sulfate
Manufacturers' Codes: RP-3554
Trademarks: Multergan (Specia); Padisal (Bayer)
Molecular Formula: C19H26N2O4S2
Molecular Weight: 410.55
Percent Composition: C 55.58%, H 6.38%, N 6.82%, O 15.59%, S 15.62%
Literature References: Prepd by treating promethazine with dimethyl sulfate: GB 641452 (1950 to Rh?ne-Poulenc). Crystal structure: P. Marsau, Y. Cam, Acta Crystallogr. B29, 980 (1973). Determn in body fluids: J. H. G. Jonkman et al., J. Pharm. Pharmacol. 27, 849 (1975). Bioavailability: idem et al., Clin. Pharmacol. Ther. 21, 457 (1977). Pharmacokinetics: idem et al., Arzneim.-Forsch. 23, 223 (1983); idem et al., Int. J. Clin. Pharmacol. Ther. Toxicol. 21, 454 (1983).
Properties: Crystals, mp 206-210° (some dec). Discolors on exposure to light. Soly in water (25°): ~10%. Freely sol in abs ethanol; sparingly sol in acetone. Practically insol in ether, benzene.
Melting point: mp 206-210° (some dec)
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Tricyclics; Phenothiazines.