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CAS No 57982-78-2 , 1-tert-butyl-4,4-diphenylpiperidine Search by region : India

  • Name: 1-tert-butyl-4,4-diphenylpiperidine
  • Synonyms: Budipine [INN];57982-78-2; 1-tert-Butyl-4,4-diphenylpiperidine;1-tert-butyl-4,4-diphenylpiperidine; Budipinum [INN-Latin]; Budipin [German]; Budipina [INN-Spanish];
  • CAS Registry Number:
  • Flash Point: 168.7°C
  • Boiling Point: 387.6°Cat760mmHg
  • Density: 1.009g/cm3
  • Refractive index: 1.557
  • Safety Statements: Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 168.7°C
  • EINECS: 261-062-4
  • Molecular Weight: 293.44578
  • InchiKey: QIHLUZAFSSMXHQ-UHFFFAOYSA-N
  • InChI: InChI=1S/C21H27N/c1-20(2,3)22-16-14-21(15-17-22,
    18-10-6-4-7-11-18)19-12-8-5-9-13-19/h4-13H,14-17H2,1-3H3
  • Molecular Formula: C21H27N
  • Molecular Structure:CAS No:57982-78-2 1-tert-butyl-4,4-diphenylpiperidine

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References of 1-tert-butyl-4,4-diphenylpiperidine
Title: Budipine
CAS Registry Number: 57982-78-2
CAS Name: 1-(1,1-Dimethylethyl)-4,4-diphenylpiperidine
Synonyms: 1-tert-butyl-4,4-diphenylpiperidine
Molecular Formula: C21H27N
Molecular Weight: 293.45
Percent Composition: C 85.95%, H 9.27%, N 4.77%
Literature References: Centrally acting deriv of diphenylpiperidine. Prepn: H. G. Menge, J. Klosa, DE 1936452; eidem, US 4016280 (1969, 1977 both to Byk Gulden). Pharmacological studies: U. Brand, H. G. Menge, Arzneim.-Forsch. 30, 1242 (1980); M. Eltze, ibid. 1129; H. G. Menge, U. Brand, ibid. 32, 85 (1982). Comparison to other drugs in treatment of dyskinesias: J. Siegfried, Can. J. Neurol. Sci. 6, 89 (1979). Clinical evaluation with levodopa in Parkinson's disease: K. Jellinger, H. Bliesath, J. Neurol. 234, 280 (1987).
 
Derivative Type: Hydrochloride
CAS Registry Number: 63661-61-0
Trademarks: Parkinsan (Byk Gulden)
Molecular Formula: C21H27N.HCl
Molecular Weight: 329.91
Percent Composition: C 76.45%, H 8.55%, N 4.25%, Cl 10.75%
Properties: LD50 in male mice, rats (mg/kg): 120, 165 orally; 33, 28 i.v. (Menge, Brand).
Toxicity data: LD50 in male mice, rats (mg/kg): 120, 165 orally; 33, 28 i.v. (Menge, Brand)
 
Therap-Cat: Antiparkinsonian.
Keywords: Antiparkinsonian.