Title: Cymoxanil
CAS Registry Number: 57966-95-7
CAS Name: 2-Cyano-
N-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide
Synonyms: 2-cyano-
N-ethylcarbamoyl-2-methoxyiminoacetamide; 1-(2-cyano-2-methoxyiminoacetyl)-3-ethylurea
Manufacturers' Codes: DPX-3217
Trademarks: Biozate (Ind. Bioquim); Curzate (DuPont)
Molecular Formula: C7H10N4O3
Molecular Weight: 198.18
Percent Composition: C 42.42%, H 5.09%, N 28.27%, O 24.22%
Literature References: Systemic fungicide primarily for potato blight. Prepn: S. H. Davidson,
US 3957847 (1976 to DuPont). Metabolism in plants: Y. Cohen, U. Gisi,
Crop Prot. 12, 284 (1993).
In vitro sensitivity study: R. A. Hamlen, R. J. Power,
Pestic. Sci. 53, 101 (1998). GC determn in plants and food products: R. F. Holt,
ibid. 10, 455 (1979). Field trials in blight: M. Absi,
Proc. Br. Crop Prot. Conf. - Pests Dis. 1979, 311. Brief description: H. L. Klopping, C. J. Delp,
J. Agric. Food Chem. 28, 467 (1980).
Properties: Crystals from acetone, mp 160-161°. Soly in water approx. 1000 ppm. For 80% formulations, LD50 orally in male rats: 1425 mg/kg; dermally in male rabbits: >3000 mg/kg. LC50 orally in bobwhite quails, mallard ducks: 2847, >10000 ppm. LC50 (96 hr) in bluegill sunfish, rainbow trout (ppm): 13.5, 18.7 (Klopping, Delp).
Melting point: mp 160-161°
Toxicity data: For 80% formulations, LD50 orally in male rats: 1425 mg/kg; dermally in male rabbits: >3000 mg/kg. LC50 orally in bobwhite quails, mallard ducks: 2847, >10000 ppm. LC50 (96 hr) in bluegill sunfish, rainbow trout (ppm): 13.5, 18.7 (Klopping, Delp).
Use: Agricultural fungicide.