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CAS No 57808-65-8 , N-[5-chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]-2-hydroxy-
3,5-diiodobenzamide

  • Name: N-[5-chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]-2-hydroxy-
    3,5-diiodobenzamide
  • Synonyms: N-[5-chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]-2-hydroxy-
    3,5-diiodobenzamide;57808-65-8; STK378904; EINECS 260-967-1; SMR000857079; NSC 335306; Closantelum [INN-Latin]; NCGC00166312-01; MLS001332593;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 210 - 220C
  • Flash Point: 310.9°C
  • Boiling Point: 590.5°Cat760mmHg
  • Density: 1.943g/cm3
  • Refractive index: 1.736
  • Water Solubility: Insoluble
  • Safety Statements: 22,
  • Hazard Symbols: Xn:;
  • Flash Point: 310.9°C
  • EINECS: 260-967-1
  • Molecular Weight: 663.0737
  • InchiKey: JMPFSEBWVLAJKM-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)
    9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)
  • Risk Statements: 22;
  • Molecular Formula: C22H14Cl2I2N2O2
  • Molecular Structure:CAS No:57808-65-8 N-[5-chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]-2-hydroxy-<br />3,5-diiodobenzamide

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References of N-[5-chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]-2-hydroxy-
3,5-diiodobenzamide
Title: Closantel
CAS Registry Number: 57808-65-8
CAS Name: N-[5-Chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodobenzamide
Manufacturers' Codes: R-31520
Trademarks: Flukiver (Janssen); Seponver (Ethnor)
Molecular Formula: C22H14Cl2I2N2O2
Molecular Weight: 663.07
Percent Composition: C 39.85%, H 2.13%, Cl 10.69%, I 38.28%, N 4.22%, O 4.83%
Literature References: Salicylanilide derivative. Prepn: M. A. C. Janssen, V. K. Sipido, BE 839481; eidem, US 4005218 (1976, 1977 both to Janssen). Effectiveness against Taenia pisiformis in rabbits: R. A. F. Chevis et al., Vet. Parasitol. 7, 333 (1980); against Ancylostoma caninum: J. Guerrero et al., J. Parasitol. 68, 616 (1983); against Fasciola hepatica in sheep: B. E. Stromberg et al., ibid. 70, 446 (1984). Prolonged effect on Haemonchus contortus in sheep: C. A. Hall et al., Res. Vet. Sci. 31, 104 (1981). Acts by uncoupling oxidative phosphorylation: H. Van den Bossche et al., Arch. Int. Physiol. Biochim. 87, 851 (1979); H. J. Kane et al., Mol. Biochem. Parasitol. 1, 347 (1980).
Properties: Crystals from methanol, mp 217.8°.
Melting point: mp 217.8°
Therap-Cat-Vet: Anthelmintic.