Home > Name List By p > Pregna-1,4-diene-3,20-dione,17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6b,11b)-

CAS No 57781-14-3 , Pregna-1,4-diene-3,20-dione,17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6b,11b)-

  • Name: Pregna-1,4-diene-3,20-dione,17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6b,11b)-
  • Synonyms: Topicon; THS 201;Pregna-1,4-diene-3,20-dione,17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6b,11b)-;Halopredone acetate;Haloart;
  • CAS Registry Number:
  • Flash Point: 329.1°C
  • Boiling Point: 620.5°C at 760 mmHg
  • Density: 1.49g/cm3
  • Refractive index: 1.569
  • Safety Statements: Low toxicity by ingestion. An experimental teratogen. Experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F− and Br−.
  • Flash Point: 329.1°C
  • EINECS: 260-951-4
  • Molecular Weight: 559.45
  • InChI: InChI=1/C25H29BrF2O7/c1-12(29)34-11-21(33)24(35-13(2)30)6-5-14-15-7-18(27)16-8-19(31)17(26)9-23(16,4)25(15,28)20(32)10-22(14,24)3/h8-9,14-15,18,20,32H,5-7,10-11H2,1-4H3/t14-,15-,18+,20-,22-,23-,24-,25-/m0/s1
  • Molecular Formula: C25H29 Br F2 O7
  • Molecular Structure:CAS No:57781-14-3 Pregna-1,4-diene-3,20-dione,17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6b,11b)-

Related products

Select to

57781-14-3 Halopredone biacetate

Contact Supplier

57781-14-3 Pregna-1,4-diene-3,20-dione,17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6b,11b)-

Contact Supplier

57781-14-3 Pregna-1,4-diene-3,20-dione,17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6b,11b)-

Contact Supplier

57781-14-3 HALOPREDONE ACETATE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of Pregna-1,4-diene-3,20-dione,17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6b,11b)-
Title: Halopredone Acetate
CAS Registry Number: 57781-14-3
CAS Name: (6b,11b)-17,21-Bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxypregna-1,4-diene-3,20-dione
Synonyms: 2-bromo-6b,9-difluoro-11b,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-diacetate
Trademarks: Haloart (Taiho)
Molecular Formula: C25H29BrF2O7
Molecular Weight: 559.39
Percent Composition: C 53.68%, H 5.23%, Br 14.28%, F 6.79%, O 20.02%
Literature References: Prepn: M. Riva, L. Toscano, DE 2508136; M. Riva et al., US 4226862 (1975, 1980 both to Pierrel); L. Toscano et al., J. Med. Chem. 20, 213 (1977). Physico-chemical and analytical studies: eidem, Arzneim.-Forsch. 27, 1636 (1977). Pharmacology: A. Bianchetti et al., ibid. 2096. Clinical study: B. Palmerio, P. Magnani, ibid. 2404. Toxicological study: L. Casilli et al., ibid. 2102.
Properties: Crystals from benzene, mp 290-292° (dec). [a]D24 -36° (c = 1 in chloroform). uv max (methanol): 246 nm (e 12500).
Melting point: mp 290-292° (dec)
Optical Rotation: [a]D24 -36° (c = 1 in chloroform)
Absorption maximum: uv max (methanol): 246 nm (e 12500)
Therap-Cat: Anti-inflammatory (topical).
Keywords: Glucocorticoid.