Home > Name List By n > N,N-diethyl-2-[3-(1-phenylpropyl)-1,2,4-oxadiazol-5-yl]ethanamine

CAS No 5696-09-3 , N,N-diethyl-2-[3-(1-phenylpropyl)-1,2,4-oxadiazol-5-yl]ethanamine

  • Name: N,N-diethyl-2-[3-(1-phenylpropyl)-1,2,4-oxadiazol-5-yl]ethanamine
  • Synonyms: (+)-Proxazolo [Italian]; (-)-Proxazolo [Italian];N,N-diethyl-2-[3-(1-phenylpropyl)-1,2,4-oxadiazol-5-yl]ethanamine; (-)-Proxazole; BRN 0679871; (+-)-Proxazole; (+-)-Proxazolo [Italian];(+)-Proxazole;
  • CAS Registry Number:
  • Flash Point: 200°C
  • Boiling Point: 407.1°Cat760mmHg
  • Density: 1.034g/cm3
  • Refractive index: 1.524
  • Flash Point: 200°C
  • Molecular Weight: 287.3999
  • InchiKey: OLTAWOVKGWWERU-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H25N3O/c1-4-15(14-10-8-7-9-11-14)17-18-16(21-19-17)12-13-20
    (5-2)6-3/h7-11,15H,4-6,12-13H2,1-3H3
  • Molecular Formula: C17H25N3O
  • Molecular Structure:CAS No:5696-09-3 N,N-diethyl-2-[3-(1-phenylpropyl)-1,2,4-oxadiazol-5-yl]ethanamine

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5696-09-3 Proxazole

  • Proxazole, Min 99%
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References of N,N-diethyl-2-[3-(1-phenylpropyl)-1,2,4-oxadiazol-5-yl]ethanamine
Title: Proxazole
CAS Registry Number: 5696-09-3
CAS Name: N,N-Diethyl-3-(1-phenylpropyl)-1,2,4-oxadiazole-5-ethanamine
Synonyms: 5-[2-(diethylamino)ethyl]-3-(a-ethylbenzyl)-1,2,4-oxadiazole; propaxoline
Molecular Formula: C17H25N3O
Molecular Weight: 287.40
Percent Composition: C 71.04%, H 8.77%, N 14.62%, O 5.57%
Literature References: Smooth muscle relaxant. Prepn: GB 924608; Palazzo, Silvestrini, US 3141019 (1963, 1964 both to Angelini Francesco). Pharmacology: Silvestrini, Pozzatti, Arzneim.-Forsch. 13, 798 (1963). Separation and pharmacology of the enantiomers: De Feo et al., Farmaco Ed. Sci. 26, 370 (1971). Clinical trial in cerebrovascular insufficiency: G. Esposito, M. De Gregorio, Arzneim.-Forsch. 24, 1692 (1974).
Properties: bp0.2 132°.
Boiling point: bp0.2 132°
 
Derivative Type: Citrate
CAS Registry Number: 132-35-4
Manufacturers' Codes: AF-634
Trademarks: Flou (ELEA); Pirecin (Yoshitomi); Toness (Angelini)
Molecular Formula: C17H25N3O.C6H8O7
Molecular Weight: 479.52
Percent Composition: C 57.61%, H 6.94%, N 8.76%, O 26.69%
Properties: LD50 in rats (mg/kg): 39 i.p., 60 orally (Silvestrini, Pozzatti).
Toxicity data: LD50 in rats (mg/kg): 39 i.p., 60 orally (Silvestrini, Pozzatti)
 
Derivative Type: Nitrate
Properties: Crystals, mp 127-128°.
Melting point: mp 127-128°
 
Therap-Cat: Antispasmodic.
Therap-Cat-Vet: Antispasmodic.
Keywords: Antispasmodic.