Home > Name List By other > [6-(hydroxymethyl)pyridin-2-yl]methyl 2-(4-chlorophenoxy)-2-methylpropanoate

CAS No 55285-45-5 , [6-(hydroxymethyl)pyridin-2-yl]methyl
2-(4-chlorophenoxy)-2-methylpropanoate

  • Name: [6-(hydroxymethyl)pyridin-2-yl]methyl
    2-(4-chlorophenoxy)-2-methylpropanoate
  • Synonyms: Pirifibrato [INN-Spanish]; Pirifibrato; AC1L2AB7; SureCN49309; AC1Q3RF0; Pirifibratum; UNII-E82B3Z65BN;Bratenol;[6-(hydroxymethyl)pyridin-2-yl]methyl
    2-(4-chlorophenoxy)-2-methylpropanoate; Pirifibratum [INN-Latin];
  • CAS Registry Number:
  • Flash Point: 234.1°C
  • Boiling Point: 463.6°C at 760 mmHg
  • Density: 1.278g/cm3
  • Refractive index: 1.577
  • Flash Point: 234.1°C
  • EINECS: 244-439-8
  • Molecular Weight: 335.78212
  • InchiKey: YJBIJSVYPHRVCI-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H18ClNO4/c1-17(2,
    23-15-8-6-12(18)7-9-15)16(21)22-11-14-5-3-4-13(10-20)19-14/h3-9,20H,
    10-11H2,1-2H3
  • Molecular Formula: C17H18ClNO4
  • Molecular Structure:CAS No:55285-45-5 [6-(hydroxymethyl)pyridin-2-yl]methyl<br />2-(4-chlorophenoxy)-2-methylpropanoate

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55285-45-5 PIRIFIBRATE

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References of [6-(hydroxymethyl)pyridin-2-yl]methyl
2-(4-chlorophenoxy)-2-methylpropanoate
Title: Pirifibrate
CAS Registry Number: 55285-45-5
CAS Name: 2-(4-Chlorophenoxy)-2-methylpropanoic acid [6-(hydroxymethyl)-2-pyridinyl]methyl ester
Synonyms: 2,6-pyridinedimethanol mono-p-chlorophenoxyisobutyrate
Manufacturers' Codes: EL-466
Trademarks: Bratenol (Elmu)
Molecular Formula: C17H18ClNO4
Molecular Weight: 335.78
Percent Composition: C 60.81%, H 5.40%, Cl 10.56%, N 4.17%, O 19.06%
Literature References: Hypolipemic agent related structurally to clofibrate, q.v. Prepn: D. Humbert, R. Ratouis, DE 2432322; eidem, US 3971798 (1975, 1976 both to Roussel). Multicenter study in hyperlipoproteinemias: A. J. Domingo et al., Clin. Ther. 3, 219 (1980).
Properties: Crystals from isopropyl ether, mp 46°. LD50 in mice (mg/kg): 915-1098 i.p. (Humbert, Ratouis, 1975).
Melting point: mp 46°
Toxicity data: LD50 in mice (mg/kg): 915-1098 i.p. (Humbert, Ratouis, 1975)
 
Derivative Type: Hydrochloride
Molecular Formula: C17H18ClNO4.HCl
Molecular Weight: 372.24
Percent Composition: C 54.85%, H 5.14%, Cl 19.05%, N 3.76%, O 17.19%
Properties: Crystals, mp 110°. LD50 (calculated as base) in mice (mg/kg): 1098-1281 i.p. (Humbert, Ratouis, 1975).
Melting point: mp 110°
Toxicity data: LD50 (calculated as base) in mice (mg/kg): 1098-1281 i.p. (Humbert, Ratouis, 1975)
 
Therap-Cat: Antilipemic.
Keywords: Antilipemic; Fibrates.