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CAS No 541-19-5 , trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]
azanium Search by region : Germany

  • Name: trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]
    azanium
  • Synonyms: Diacetylcholine iodide; Curacit; O,O-Succinyldicholine iodide;trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]
    azanium; Ditilin iodide; kuratsit;Celocurine; Ascuron; Suxamethonium iodide;diiodide; Celocurin;
  • CAS Registry Number:
  • EINECS: 208-770-1
  • Molecular Weight: 544.20794
  • InchiKey: QMJHHGXCWYZSBV-UHFFFAOYSA-L
  • InChI: InChI=1S/C14H30N2O4.2HI/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,
    5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
  • Molecular Formula: C14H30I2N2O4
  • Molecular Structure:CAS No:541-19-5 trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]<br />azanium

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541-19-5 o,o-Succinyldicholine iodide

  • o,o-Succinyldicholine iodide
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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References of trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]
azanium
Title: Succinylcholine Iodide
CAS Registry Number: 541-19-5
Synonyms: O,O-Succinyldicholine iodide; diacetylcholine iodide; diacetylcholine diiodide; suxamethonium iodide; bis(b-dimethylaminoethyl)succinate bis(methyl iodide)
Trademarks: Celocurine (Pfizer)
Molecular Formula: C14H30I2N2O4
Molecular Weight: 544.21
Percent Composition: C 30.90%, H 5.56%, I 46.64%, N 5.15%, O 11.76%
Literature References: Prepd by reacting b-bromoethyl succinate with trimethylamine: Glick, J. Biol. Chem. 137, 357 (1941); Fusco et al., Gazz. Chim. Ital. 79, 129, 837 (1949); Walker, J. Chem. Soc. 1950, 193. Succinic acid chloride may be coupled with choline chloride directly or with dimethylaminoethanol, followed by quaternization with methyl iodide: Tammelin, Acta Chem. Scand. 7, 185 (1953). A third method is to start with the diethyl ester of succinic acid, then bring about the exchange reaction with dimethylaminoethanol, and quaternize with methyl iodide: Phillips, J. Am. Chem. Soc. 71, 3264 (1949).
Properties: Slightly hygroscopic crystals, mp 243-245°. Freely sol in water or normal saline, giving solns which are very slightly acidic. Most stable at pH 4-5. Aq solns undergo progressive hydrolysis with corresp loss of activity and increase in acidity. Prepare solns just before using. Incompatible with solns of alkaline salts.
Melting point: mp 243-245°
Therap-Cat: Neuromuscular blocking agent.
Therap-Cat-Vet: Muscle relaxant (skeletal).
Keywords: Neuromuscular Blocking Agent; Depolarizing Agents.