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CAS No 53882-12-5 , Lodoxamide

  • Name: Lodoxamide
  • Synonyms: Lodoxamidum [inn-latin];N,N'-(2-Chlor-5-cyan-3-phenylen)dioxamsaeure;Lodoxamidum;Lodoxamida [inn-spanish];Acetic acid, 2,2'-((2-chloro-5-cyano-1,3-phenylene)diimino)bis(2-oxo-;2,2'-[(2-Chloro-5-cyano-1,3-phenylene)diimino]bis[2-oxoacetic acid];Lodoxamide;Unii-spu695od73;Lodoxamida;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.78g/cm3
  • Refractive index: 1.673
  • Flash Point: °C
  • Molecular Weight: 0
  • InChI: InChI=1/C11H6ClN3O6/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21)
  • Molecular Formula: C11H6ClN3O6
  • Molecular Structure:CAS No:53882-12-5 Lodoxamide
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53882-12-5 LODOXAMIDE

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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53882-12-5 Lodoxamide Tromethamine

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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53882-12-5 Lodoxamide Tromethamine

  • India Triveni Chemicals null
  • Tel: +91-(260)-2400022, 3258683
  • Fax: +91-(260)-2400022/3264008
  • Address: 135, Pancharatna, Char Rasta, G.I.D.C., Vapi, Gujarat 396 195, null,nullIndia
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53882-12-5 LODOXAMIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of Lodoxamide
Title: Lodoxamide
CAS Registry Number: 53882-12-5
CAS Name: 2,2￠-[(2-Chloro-5-cyano-1,3-phenylene)diimino]bis(2-oxoacetic acid)
Synonyms: N,N￠-(2-chloro-5-cyano-m-phenylene)dioxamic acid
Molecular Formula: C11H6ClN3O6
Molecular Weight: 311.63
Percent Composition: C 42.40%, H 1.94%, Cl 11.38%, N 13.48%, O 30.80%
Literature References: Mast cell stabilizer. Prepn: C. M. Hall, J. B. Wright, DE 2362409; eidem, US 3993679 (1974, 1976 both to Upjohn); J. B. Wright et al., J. Med. Chem. 21, 930 (1978). HPLC determn in human plasma: I. L. Honigberg et al., J. Chromatogr. 276, 213 (1983). Mechanism of action study: M. K. Church, J. Hiroi, Br. J. Pharmacol. 90, 421 (1987). Clinical evaluation in asthma: R. L. Case et al., J. Am. Med. Assoc. 247, 661 (1982); in allergic eye disease: G. T. Fahy et al., Eur. J. Ophthalmol. 2, 144 (1992).
Properties: mp 212° (dec). uv max (0.1N NaOH) 239.5 (e 23800).
Melting point: mp 212° (dec)
Absorption maximum: uv max (0.1N NaOH) 239.5 (e 23800)
 
Derivative Type: Diethyl ester
CAS Registry Number: 53882-13-6
Synonyms: Diethyl N,N￠-(2-chloro-5-cyano-m-phenylene)dioxamate; lodoxamide ethyl
Manufacturers' Codes: U-42718
Molecular Formula: C15H14ClN3O6
Molecular Weight: 367.74
Percent Composition: C 48.99%, H 3.84%, Cl 9.64%, N 11.43%, O 26.10%
Properties: Crystals from ethanol, mp 177-179°.
Melting point: mp 177-179°
 
Derivative Type: Tromethamine salt
CAS Registry Number: 63610-09-3
Synonyms: Lodoxamide tromethamine; lodoxamide trometamol
Manufacturers' Codes: U-42585E
Trademarks: Alomide (Alcon)
Molecular Formula: C11H6ClN3O6.2C4H11NO3
Molecular Weight: 553.90
Percent Composition: C 41.20%, H 5.10%, Cl 6.40%, N 12.64%, O 34.66%
 
Therap-Cat: Antiallergic; topically in allergic conjunctivitis.
Keywords: Antiallergic.