CAS No 537-21-3 , chlorproguanil

Name: chlorproguanil
Synonyms: 1-(3,4-dichlorophenyl)-5-isopropylbiguanide;chlorproguanil;
CAS Registry Number:537-21-3
EINECS: 208-660-3
Molecular Weight: 288.1759
InChI: InChI=1S/C11H15Cl2N5/c1-6(2)16-10(14)18-11(15)17-7-3-4-8(12)9(13)5-7/h3-6H,1-2H3,(H5,14,15,16,17,18)
Molecular Formula: C₁₁H₁₅Cl₂N₅
Molecular Structure:

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           537-21-3 Chlorproguanil
           
             Manus Aktteva
             
              null
Tel: +91-(79)-65123395
Fax: +91-(79)-26463395
Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006,  null,nullIndia

           537-21-3 CHLORPROGUANIL-D6
           
             VARDA Biotech (P) Ltd.
             
              [Manufacturer]
Tel:  +91-22-6693 5686 / 2673 0141 / 2673 4258
Fax:  +91-22-6693 5687
Address:  110 & 111, Kartik Complex
New link Road, Andheri-(W)
Mumbai-400053, INDIA. null,nullIndia

           537-21-3 CHLORPROGUANIL
           
             Nanjing Chemlin Chemical Industry Co.,Ltd.
             
              [Manufacturer]
Tel:  +86 25 8369-7070/ +86 138 51816776 (Mobile)
Fax:  +86 25 8345-3275
Address: Rm.902 Longyin Plaza,
No. 217 Zhongshan Rd.
(N)Nanjing 210009,China null,nullChina

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References of chlorproguanil

Title: Chlorproguanil
CAS Registry Number: 537-21-3
CAS Name: N-(3,4-Dichlorophenyl)-N￠-(1-methylethyl)imidodicarbonimidic diamide
Synonyms: 1-(3,4-dichlorophenyl)-5-isopropylbiguanide; N1-3,4-dichlorophenyl-N5-isopropylbiguanide; N1-3,4-dichlorophenyl-N5-isopropyldiguanide
Manufacturers' Codes: M-5943
Molecular Formula: C11H15Cl2N5
Molecular Weight: 288.18
Percent Composition: C 45.85%, H 5.25%, Cl 24.60%, N 24.30%
Literature References: Method of prepn: Crowther et al., J. Chem. Soc. 1951, 1780; Curd et al., US 2544827 (1951); Crowther et al., GB 667116 (1952) (both to ICI). Clinical trial with dapsone, q.v., in drug-resistant malaria: T. Mutabingwa et al., Lancet 358, 1218 (2001).

Derivative Type: Hydrochloride
CAS Registry Number: 15537-76-5
Trademarks: Lapudrine (Zeneca)
Molecular Formula: C11H15Cl2N5.HCl
Molecular Weight: 324.64
Percent Composition: C 40.70%, H 4.97%, Cl 32.76%, N 21.57%
Properties: Crystals, mp 246-247°. Soly in water: 1 g/100 ml. Solns may be boiled without dec.
Melting point: mp 246-247°

Therap-Cat: Antimalarial.
Keywords: Antimalarial.