References of 3-Pyridinecarboxylicacid, (1R,5S)-3,3,5-trimethylcyclohexyl ester, rel-
Title: Ciclonicate
CAS Registry Number: 53449-58-4
CAS Name: 3-Pyridinecarboxylic acid 3,3,5-trimethylcyclohexyl ester
Synonyms: trans-3,3,5-trimethylcyclohexyl nicotinate; cyclonicate
Manufacturers' Codes: P-350
Trademarks: Bled (Poli)
Molecular Formula: C15H21NO2
Molecular Weight: 247.33
Percent Composition: C 72.84%, H 8.56%, N 5.66%, O 12.94%
Literature References: Deriv of nicotinic acid,
q.v. Prepn: K. Matsuda
et al., DE 1910481 (1969 to Takeda),
C.A. 72, 12769g (1970); G. Massaroli,
DE 2406849 (1974 to Poli),
C.A. 82, 4129 (1975). Chromatographic study: G. Sekules
et al., Boll. Chim. Farm. 119, 521 (1980). Antilipolytic activity in rats: D. Faini
et al., Farmaco Ed. Prat. 36, 478 (1981).
In vitro effect on lipolysis: F. Tessari
et al., Farmaco Ed. Sci. 36, 1029 (1981). Clinical study: C. Fossati,
Gazz. Med. Ital. 139, 43 (1980).
Properties: Liq, bp0.6 127-128°.
Boiling point: bp0.6 127-128°
Therap-Cat: Vasodilator.
Keywords: Vasodilator (Cerebral); Vasodilator (Peripheral).