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CAS No 53267-01-9 , 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole

  • Name: 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
  • Synonyms: Cibenzolina [INN-Spanish]; Cibenzolinum [INN-Latin];Cibenzoline; 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole; Cifenline;2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole; 53267-01-9;
  • CAS Registry Number:
  • Flash Point: 225.5 ºC
  • Boiling Point: 449.2 ºC
  • Density: 1.17 g/cm3
  • Refractive index: 1.655
  • Flash Point: 225.5 ºC
  • EINECS: 258-453-7
  • Molecular Weight: 262.34892
  • InchiKey: IPOBOOXFSRWSHL-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H18N2/c1-3-7-14(8-4-1)18(15-9-5-2-6-10-15)13-16(18)17-19-11-
    12-20-17/h1-10,16H,11-13H2,(H,19,20)
  • Molecular Formula: C18H18N2
  • Molecular Structure:CAS No:53267-01-9 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole

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References of 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
Title: Cifenline
CAS Registry Number: 53267-01-9
CAS Name: 2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
Synonyms: (±)-2-(2,2-diphenylcyclopropyl)-2-imidazoline; 1-(2-D2-imidazolinyl)-2,2-diphenylcyclopropane; cibenzoline
Manufacturers' Codes: Ro-22-7796; UP-33-901
Molecular Formula: C18H18N2
Molecular Weight: 262.35
Percent Composition: C 82.41%, H 6.92%, N 10.68%
Literature References: Prepn: BE 807630; J. C. Cognaco, US 3903104 (1974, 1975 both to Hexachemie). Activity and tolerance: D. Herpin et al., Acta Cardiol. 36, 131 (1981). Electrophysiological effects in man: J. F. Thizy et al., Lyon Med. 245, 119 (1981). Clinical trial: D. Herpin et al., Curr. Ther. Res. 30, 742 (1981).
Properties: Crystals from petr ether, mp 103-104°. LD100 in rats (mg/kg): 64 i.v. (Cognaco).
Melting point: mp 103-104°
Toxicity data: LD100 in rats (mg/kg): 64 i.v. (Cognaco)
 
Derivative Type: Succinate
CAS Registry Number: 100678-32-8
Trademarks: Cibenol (Fujisawa); Cipralan (Roche); Exacor (Searle)
Molecular Formula: C18H18N2.C4H6O4
Molecular Weight: 380.44
Percent Composition: C 69.46%, H 6.36%, N 7.36%, O 16.82%
Properties: Crystals from ethanol + ether, mp 165°.
Melting point: mp 165°
 
Therap-Cat: Antiarrhythmic.
Keywords: Antiarrhythmic.