CAS No 5310-55-4 , Clomacran

Name: Clomacran
Synonyms: SKF-14336D;SKF-14336;2-Chloro-9-[3-(dimethylamino)propyl]acridan;Clomacran;
CAS Registry Number:5310-55-4
Flash Point: 197.2°C
Boiling Point: 402.4°C at 760 mmHg
Density: 1.12g/cm³
Refractive index: 1.577
Flash Point: 197.2°C
Molecular Weight: 300.831
InChI: InChI=1S/C18H21ClN2/c1-21(2)11-5-7-14-15-6-3-4-8-17(15)20-18-10-9-13(19)12-16(14)18/h3-4,6,8-10,12,14,20H,5,7,11H2,1-2H3
Molecular Formula: C18H21ClN2
Molecular Structure:

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           5310-55-4 Clomacran
           Clomacran, Min 99%
 
             Finechemie Co., Ltd. 
             
              [Manufacturer]
Tel: +86-23-99186710 
Fax: +86-23-99186729 
Address: 28th Floor Mordern Building,New-Tech Zone400020  ChongqingCHINA Chongqing,nullChina

           5310-55-4 Clomacran
           Clomacran, 99%
 
             Facus Pharmaceutical Co., Ltd. 
             
              [Manufacturer]
Tel: +86-(0)574-62378411   
Fax: +86-(0)574-62378410  
Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 
 
315800  NingboCHINA Ningbo,nullChina

           5310-55-4 CLOMACRAN
           
             Nanjing Chemlin Chemical Industry Co.,Ltd.
             
              [Manufacturer]
Tel:  +86 25 8369-7070/ +86 138 51816776 (Mobile)
Fax:  +86 25 8345-3275
Address: Rm.902 Longyin Plaza,
No. 217 Zhongshan Rd.
(N)Nanjing 210009,China null,nullChina

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References of Clomacran

Title: Clomacran
CAS Registry Number: 5310-55-4
CAS Name: 2-Chloro-9,10-dihydro-N,N-dimethyl-9-acridinepropanamine
Synonyms: 2-chloro-9-[3-(dimethylamino)propyl]acridan
Manufacturers' Codes: SKF-14336D
Molecular Formula: C18H21ClN2
Molecular Weight: 300.83
Percent Composition: C 71.87%, H 7.04%, Cl 11.79%, N 9.31%
Literature References: Prepn: C. L. Zirkle, US 3131190 (1964 to SKF). Effect on in vivo histamine metabolism: R. Schayer, M. A. Reilly, Arch. Int. Pharmacodyn. Ther. 203, 123 (1973). Clinical potency in relation to dopamine-binding: P. Seeman et al., Nature 261, 717 (1976). Pharmacology: P. Fowler et al., Arzneim.-Forsch. 27, 866 (1977). Photooxidation study: W. R. Knappe, J. Pharm. Sci. 67, 318 (1978).

Derivative Type: Phosphate
CAS Registry Number: 22199-46-8
Manufacturers' Codes: SKF-14336
Trademarks: Devryl (SK & F); Olaxin (SK & F)
Molecular Formula: C18H21ClN2.H3PO4
Molecular Weight: 398.82
Percent Composition: C 54.21%, H 6.07%, Cl 8.89%, N 7.02%, P 7.77%, O 16.05%
Properties: LD50 in rats, mice (mg/kg): 350, 222 orally (Fowler).
Toxicity data: LD50 in rats, mice (mg/kg): 350, 222 orally (Fowler)

Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Other Tricyclics.

Status: This monograph has been retired and is no longer subject to revision or update.