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CAS No 53-46-3 , diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium

  • Name: diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium
  • Synonyms: bromide; Gastrosedan; Asabaine; Resobantin; Methelina; Banthine;diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium; Frenogastrico; Doladene; Dixamone bromide;METHANTHELINE BROMIDE; Metantyl;
  • CAS Registry Number:
  • Melting Point: 420.34
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Safety Statements: Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Unspecified human reproductive effects. When heated to decomposition it emits very toxic fumes of NOx, NH3, and Br−.
  • Flash Point: °C
  • EINECS: 200-176-0
  • Molecular Weight: 420.34004
  • InchiKey: PQMWYJDJHJQZDE-UHFFFAOYSA-M
  • InChI: InChI=1S/C21H26NO3.BrH/c1-4-22(3,
    5-2)14-15-24-21(23)20-16-10-6-8-12-18(16)25-19-13-9-7-11-17(19)20;/h6-
    13,20H,4-5,14-15H2,1-3H3;1H/q+1;/p-1
  • Molecular Formula: C21H26BrNO3
  • Molecular Structure:CAS No:53-46-3 diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium

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53-46-3 GASTRIC MUCIN

  • China CHONGQING TRUST LONG CO.,LTD. null
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  • Address: 3-6-2, No.1, Xinglong Road, Longxi Town, Yubei Dist.,Chongqing,China null,nullChina
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53-46-3 Gastric Mucin

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53-46-3 METHANTHELINE BROMIDE (200 MG)

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
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  • Address: Rm.902 Longyin Plaza,
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References of diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium
Title: Methantheline Bromide
CAS Registry Number: 53-46-3
CAS Name: N,N-Diethyl-N-methyl-2-[(9H-xanthen-9-ylcarbonyl)oxy]ethanaminium bromide
Synonyms: diethyl(2-hydroxyethyl)methylammonium bromide xanthene-9-carboxylate; b-diethylaminoethyl 9-xanthenecarboxylate methobromide
Manufacturers' Codes: MTB-51; SC-2910
Trademarks: Banthine Bromide (Searle); Avagal; Uldumont; Vagantin; Metaxan; Methanide; Xanteline; Gastron (Winthrop); Gastrosedan; Methanthine Bromide; Vagamin; Metanyl; Doladene; Asabaine
Molecular Formula: C21H26BrNO3
Molecular Weight: 420.34
Percent Composition: C 60.00%, H 6.23%, Br 19.01%, N 3.33%, O 11.42%
Literature References: Anticholinergic. Prepn from 9-xanthenecarboxylic acid and 2-diethylaminoethanol: J. W. Cusic, R. A. Robinson, J. Org. Chem. 16, 1921 (1951); eidem, US 2659732 (1952 to Searle). Pharmacology: W. E. Hambourger et al., J. Pharmacol. Exp. Ther. 99, 245 (1950).
Properties: Crystals from isopropanol, mp 175-176°. Bitter taste. Very slightly hygroscopic. Freely sol in water, alcohol. Practically insol in ether. pH (2% aq soln): 5.0-5.5. Aq solns tend to hydrolyze after a few days. The corresponding chloride is very hygroscopic. uv max (alc): 246, 282 nm (E1%1cm 135, 69). LD50 i.p. in mice: 76 mg/kg (Hambourger).
Melting point: mp 175-176°
Absorption maximum: uv max (alc): 246, 282 nm (E1%1cm 135, 69)
Toxicity data: LD50 i.p. in mice: 76 mg/kg (Hambourger)
Therap-Cat: Antispasmodic. In treatment of urinary incontinence.
Keywords: Antispasmodic; Antimuscarinic.