Title: Apronalide
CAS Registry Number: 528-92-7
CAS Name: N-(Aminocarbonyl)-2-(1-methylethyl)-4-pentenamide
Synonyms: (2-isopropyl-4-pentenoyl)urea; allylisopropylacetylurea
Trademarks: Apronal (Baxter); Sedormid (Roche)
Molecular Formula: C9H16N2O2
Molecular Weight: 184.24
Percent Composition: C 58.67%, H 8.75%, N 15.20%, O 17.37%
Literature References: Prepn: Slotta,
Grundriss der modernen Arzneistoff-Synthese (Stuttgart, 1931) p 35.
Properties: Crystals. Practically tasteless. mp 194°. One gram dissolves in 3000 ml cold water, in 210 ml boiling water. One part dissolves in 10 parts alc, 75 parts ether. Decolorizes KMnO4 solns.
Melting point: mp 194°
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Acylic Ureides.
Status: This monograph has been retired and is no longer subject to revision or update.