Home > Name List By 2 > 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R,3R,4S,5R)-3, 4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide

CAS No 52443-21-7 , 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R,3R,4S,5R)-3,
4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide

  • Name: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R,3R,4S,5R)-3,
    4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide
  • Synonyms: Teoremac; Glucometacin;2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R,3R,4S,5R)-3,
    4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide; Glucametacine [INN-French]; Glucametacina [INN-Spanish];Glucametacine; Glucametacinum [INN-Latin];
  • CAS Registry Number:
  • Flash Point: 433.8°C
  • Boiling Point: 793.7°Cat760mmHg
  • Density: 1.44
  • Refractive index: 1.634
  • Flash Point: 433.8°C
  • EINECS: 257-923-9
  • Molecular Weight: 518.94348
  • InchiKey: XLVXAUNDHWERBM-IVGWJTKZSA-N
  • InChI: InChI=1S/C25H27ClN2O8/c1-13-17(10-22(32)27-19(11-29)23(33)24(34)21(31)
    12-30)18-9-16(36-2)7-8-20(18)28(13)25(35)14-3-5-15(26)6-4-14/h3-9,11,19,
    21,23-24,30-31,33-34H,10,12H2,1-2H3,(H,27,32)/t19-,21+,23+,24+/m0/s1
  • Molecular Formula: C25H27ClN2O8
  • Molecular Structure:CAS No:52443-21-7 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R,3R,4S,5R)-3,<br />4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide

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References of 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R,3R,4S,5R)-3,
4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide
Title: Glucametacin
CAS Registry Number: 52443-21-7
CAS Name: 2-[[[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-D-glucose
Synonyms: 2-[2-[1-(p-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetamido]-2-deoxy-D-glucose; glucametacine; glucamethacin; indomethacin glucosamide
Molecular Formula: C25H27ClN2O8
Molecular Weight: 518.94
Percent Composition: C 57.86%, H 5.24%, Cl 6.83%, N 5.40%, O 24.66%
Literature References: Deriv of indomethacin, q.v. Prepn: A. Demetrio et al., DE 2223051 (1973 to SIR Lab. Chem. Biol. SpA), C.A. 80, 83529e (1974). Pharmacological study: E. Paroli et al., Arzneim.-Forsch. 28, 819 (1978). Clinical studies: P. Petera et al., Int. J. Clin. Pharmacol. Biopharm. 15, 581 (1977); L. Capelli et al., Curr. Med. Res. Opin. 7, 227 (1981).
 
Derivative Type: Monohydrate
Trademarks: Euminex (Lacer); Teorema (Panchemie); Teoremac (Farmades)
Molecular Formula: C25H27ClN2O8.H2O
Molecular Weight: 536.96
Percent Composition: C 55.92%, H 5.44%, Cl 6.60%, N 5.22%, O 26.82%
 
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Arylacetic Acid Derivatives.