CAS No 524-83-4 , 8-Azabicyclo[3.2.1]octane,3-(diphenylmethoxy)-8-ethyl-, (3-endo)-

Name: 8-Azabicyclo[3.2.1]octane,3-(diphenylmethoxy)-8-ethyl-, (3-endo)-
Synonyms: N-Ethylnortropine benzhydryl ether;Ponalide;Etybenzatropine; Ponalid; Panolid; UK 738;8-Azabicyclo[3.2.1]octane, 3-(diphenylmethoxy)-8-ethyl-, endo-; Ethylbenztropine;3-(Diphenylmethoxy)-8-ethylnortropane;N-Ethylbenztropine;3-(Diphenylmethoxy)-8-ethyl-8-azabicyclo[3.2.1]octane; N-Ethyl-8-aza-3-bicyclo[3.2.1]octyl benzhydryl ether;1aH,5aH-Nortropane, 3a-(diphenylmethoxy)-8-ethyl- (8CI);8-Azabicyclo[3.2.1]octane,3-(diphenylmethoxy)-8-ethyl-, (3-endo)-; Ethybenztropine; Tropethydrylin;
CAS Registry Number:524-83-4
Flash Point: 124°C
Boiling Point: 422.8°Cat760mmHg
Density: 1.1g/cm³
Refractive index: 1.597
Safety Statements: Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x. See also ETHERS.
Flash Point: 124°C
Molecular Weight: 321.50
InChI: InChI=1/C22H27NO/c1-2-23-19-13-14-20(23)16-21(15-19)24-22(17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-12,19-22H,2,13-16H2,1H3/t19-,20-/m1/s1
Molecular Formula: C22H27 N O
Molecular Structure:

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References of 8-Azabicyclo[3.2.1]octane,3-(diphenylmethoxy)-8-ethyl-, (3-endo)-

Title: Ethybenztropine
CAS Registry Number: 524-83-4
CAS Name: (3-endo-)-3-(Diphenylmethoxy)-8-ethyl-8-azabicyclo[3.2.1]octane
Synonyms: 3a-(diphenylmethoxy)-8-ethyl-1aH,5aH-nortropane; N-ethylnortropine benzhydryl ether; tropethydrylin; N-ethyl-8-aza-3-bicyclo[3.2.1]octyl benzhydryl ether; N-ethylbenztropine; ethylbenzatropine; etybenzatropine
Molecular Formula: C22H27NO
Molecular Weight: 321.46
Percent Composition: C 82.20%, H 8.47%, N 4.36%, O 4.98%
Literature References: Anticholinergic. Prepn: GB 804837 (1958 to Sandoz); Boehringer et al., GB 824875 (1959 to Boehringer, Ing.).

Derivative Type: Hydrochloride
CAS Registry Number: 26598-44-7
Trademarks: Ponalide (Novartis)
Molecular Formula: C22H27NO.HCl
Molecular Weight: 357.92
Percent Composition: C 73.83%, H 7.89%, N 3.91%, O 4.47%, Cl 9.91%
Properties: Crystals from acetone, mp 190-191°.
Melting point: mp 190-191°

Derivative Type: Hydrobromide
CAS Registry Number: 24815-25-6
Molecular Formula: C22H27NO.HBr
Molecular Weight: 402.37
Percent Composition: C 65.67%, H 7.01%, N 3.48%, O 3.98%, Br 19.86%
Properties: Crystals from methanol + ether, mp 226-228°.
Melting point: mp 226-228°

Therap-Cat: Antiparkinsonian.
Keywords: Antiparkinsonian; Antimuscarinic.