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CAS No 523-54-6 , 3-(2-ethylphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine

  • Name: 3-(2-ethylphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
  • Synonyms: Nuital;3-(2-ethylphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine; 3737-33-5; NSC169471;Ethylisobutrazine; Diquel; Ethyl isobutrazine; Etymemazine [INN]; Ethotrimeprazine; 523-54-6;
  • CAS Registry Number:
  • Density: 1.085 g/cm3
  • Refractive index: 1.593
  • Molecular Weight: 326.49884
  • InchiKey: USKHCLAXJXCWMO-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H26N2S/c1-5-16-10-11-20-18(12-16)22(14-15(2)13-21(3)4)17-8-
    6-7-9-19(17)23-20/h6-12,15H,5,13-14H2,1-4H3
  • Molecular Formula: C20H26N2S
  • Molecular Structure:CAS No:523-54-6 3-(2-ethylphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine

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References of 3-(2-ethylphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
Title: Etymemazine
CAS Registry Number: 523-54-6
CAS Name: 2-Ethyl-N,N,b-trimethyl-10H-phenothiazine-10-propanamine
Synonyms: 10-[3-(dimethylamino)-2-methylpropyl]-2-ethylphenothiazine; 3-ethyl-10-(3-dimethylamino-2-methylpropyl)phenothiazine; 3-(3-ethyl-10-phenothiazinyl)-2-methyl-1-dimethylaminopropane; ethotrimeprazine; ethylisobutrazine
Manufacturers' Codes: RP-6484
Trademarks: Diquel
Molecular Formula: C20H26N2S
Molecular Weight: 326.50
Percent Composition: C 73.57%, H 8.03%, N 8.58%, S 9.82%
Literature References: Prepn: Jacob, Robert, US 2837518 (1958 to Rh?ne-Poulenc). Activity studies in pigs: Lambrerth, Aust. Vet. J. 44, 333 (1968). Biotransformation studies: Robinson, J. Pharm. Pharmacol. 18, 19 (1966).
 
Derivative Type: Hydrochloride
CAS Registry Number: 3737-33-5
Trademarks: Nuital (Vaillant-Defresne); Sergetyl (Vaillant-Defresne)
Molecular Formula: C20H26N2S.HCl
Molecular Weight: 362.96
Percent Composition: C 66.18%, H 7.50%, N 7.72%, S 8.83%, Cl 9.77%
Properties: mp 160-163°. Soluble in water, ethanol, methanol, acetone, chloroform. Practically insol in ether.
Melting point: mp 160-163°
 
Therap-Cat: Antihistaminic.
Therap-Cat-Vet: Tranquilizer.
Keywords: Antihistaminic; Tricyclics; Phenothiazines.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.