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CAS No 52214-84-3 , 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid

  • Name: 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
  • Synonyms: Hiperlipen; Modalim; Lipanor; Ciprofibratum [INN-Latin]; Ciprofibratum; Ciprofibrato; Ciprol;52214-84-3;2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid;
  • CAS Registry Number:
  • Melting Point: 114 - 118
  • Density: 1.37 g/cm3
  • Refractive index: 1.579
  • Safety Statements: R45
  • Hazard Symbols: T: Toxic;
  • EINECS: 257-744-6
  • Molecular Weight: 289.15446
  • InchiKey: KPSRODZRAIWAKH-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,
    14)15/h3-6,10H,7H2,1-2H3,(H,16,17)
  • Risk Statements: S53;S22;S36/37/39;S45
  • Molecular Formula: C13H14Cl2O3
  • Molecular Structure:CAS No:52214-84-3 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid

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References of 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
Title: Ciprofibrate
CAS Registry Number: 52214-84-3
CAS Name: 2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
Synonyms: 2-[4-(2,2-dichlorocyclopropyl)phenoxy]isobutyric acid
Manufacturers' Codes: Win-35833
Trademarks: Ciprol (Sterling); Lipanor (Winthrop); Modalim (Sanofi)
Molecular Formula: C13H14Cl2O3
Molecular Weight: 289.15
Percent Composition: C 54.00%, H 4.88%, Cl 24.52%, O 16.60%
Literature References: Hypolipemic agent, related structurally to clofibrate, q.v. Prepn: D. K. Phillips, DE 2343606 ; idem, US 3948973 (1974, 1976 both to Sterling). Pharmacokinetics in animals and man: C. Davison et al., Drug Metab. Dispos. 3, 520 (1975). Inhibition of cholesterol biosynthesis in rats: A. Arnold et al., Atherosclerosis 32, 155 (1979). Blood levels, distribution, duration of action: J. Edelson et al., ibid. 33, 351 (1979). Metabolic effects: A. Arnold et al., J. Pharm. Sci. 68, 1557 (1979). Teratology study: H. Tuchman-Duplessis et al., Toxicology 12, 1 (1979).
Properties: Pale cream solid from hexane, mp 114-116°.
Melting point: mp 114-116°
Therap-Cat: Antilipemic.
Keywords: Antilipemic; Fibrates.