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CAS No 522-24-7 , N,N-dimethyl-2-phenothiazin-10-ylethanamine

  • Name: N,N-dimethyl-2-phenothiazin-10-ylethanamine
  • Synonyms: Ethysine; Ethysene; Phenetazine; Anergell; Ethizine;Phenethazine; Anergen; Phenethazinum; Ethyzine;N,N-dimethyl-2-phenothiazin-10-ylethanamine;
  • CAS Registry Number:
  • Flash Point: 193.3°C
  • Boiling Point: 396.1°Cat760mmHg
  • Density: 1.153g/cm3
  • Refractive index: 1.628
  • Flash Point: 193.3°C
  • EINECS: 208-325-1
  • Molecular Weight: 270.39252
  • InchiKey: PFAXACNYGZVKMX-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H18N2S/c1-17(2)11-12-18-13-7-3-5-9-15(13)19-16-10-6-4-8-14
    (16)18/h3-10H,11-12H2,1-2H3
  • Molecular Formula: C16H18N2S
  • Molecular Structure:CAS No:522-24-7 N,N-dimethyl-2-phenothiazin-10-ylethanamine

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References of N,N-dimethyl-2-phenothiazin-10-ylethanamine
Title: Fenethazine
CAS Registry Number: 522-24-7
CAS Name: N,N-Dimethyl-10H-phenothiazine-10-ethanamine
Synonyms: 10-(b-dimethylaminoethyl)phenothiazine
Manufacturers' Codes: RP-3015; SC-1627
Trademarks: Anergan; Anergen; Ethysine; Etisine; Lisergan; Lysergan; Phenethazinum; Rutergan
Molecular Formula: C16H18N2S
Molecular Weight: 270.39
Percent Composition: C 71.07%, H 6.71%, N 10.36%, S 11.86%
Literature References: Prepd by the condensation of phenothiazine with dimethylaminoethyl chloride: Charpentier, US 2519886 (1950 to Rh?ne-Poulenc). Pharmacology: C. A. Winter, J. Pharmacol. Exp. Ther. 90, 224 (1947); A. von Schlichtegroll, Arzneim.-Forsch. 8, 489 (1958).
Properties: bp1 183-187°.
Boiling point: bp1 183-187°
 
Derivative Type: Hydrochloride
CAS Registry Number: 5934-20-3
Molecular Formula: C16H18N2S.HCl
Molecular Weight: 306.85
Percent Composition: C 62.63%, H 6.24%, N 9.13%, S 10.45%, Cl 11.55%
Properties: mp 201-201.5°. LD50 i.p. in mice: 140 ±13 mg/kg (Winter). LD50 orally in mice: 364 ±30 mg/kg (von Schlichtegroll).
Melting point: mp 201-201.5°
Toxicity data: LD50 i.p. in mice: 140 ±13 mg/kg (Winter); LD50 orally in mice: 364 ±30 mg/kg (von Schlichtegroll)
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Tricyclics; Phenothiazines.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.