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CAS No 51-73-0 , Pyrrolidine,1,1'-(2-butyne-1,4-diyl)bis-

  • Name: Pyrrolidine,1,1'-(2-butyne-1,4-diyl)bis-
  • Synonyms: NSC 407428;1,4-Dipyrrolidinyl-2-butyne; Tremorin;Pyrrolidine,1,1'-(2-butynylene)di- (6CI,8CI); Tremorine; 1,4-Dipyrrolidino-2-butyne;Pyrrolidine,1,1'-(2-butyne-1,4-diyl)bis-;
  • CAS Registry Number:
  • Transport: 2810
  • Flash Point: 118.4°C
  • Boiling Point: 285.6°Cat760mmHg
  • Density: 1.014g/cm3
  • Refractive index: 1.531
  • Safety Statements: Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx. See also ACETYLENE COMPOUNDS and ALKYNES.
  • Flash Point: 118.4°C
  • Molecular Weight: 192.34
  • InChI: InChI=1/C12H20N2/c1-2-8-13(7-1)11-5-6-12-14-9-3-4-10-14/h1-4,7-12H2
  • Molecular Formula: C12H20 N2
  • Molecular Structure:CAS No:51-73-0 Pyrrolidine,1,1'-(2-butyne-1,4-diyl)bis-

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1/1
References of Pyrrolidine,1,1'-(2-butyne-1,4-diyl)bis-
Title: Tremorine
CAS Registry Number: 51-73-0
CAS Name: 1,1￠-(2-Butyne-1,4-diyl)bispyrrolidine
Synonyms: 1,1￠-(2-butynylene)dipyrrolidine; 1,4-dipyrrolidino-2-butyne
Molecular Formula: C12H20N2
Molecular Weight: 192.30
Percent Composition: C 74.95%, H 10.48%, N 14.57%
Literature References: Prepn from pyrrolidine + 1,4-dichloro-2-butyne: Maier, DE 896810 (1953 to BASF); Reppe et al., Ann. 596, 79 (1955); Biel, DiPierro, J. Am. Chem. Soc. 80, 4609 (1958). Review of chemical and biological studies: Karlen, Acta Pharm. Suec. 1970, 169-200; see also Kolla, Obvintseva, Farmakol. Toksikol. 36, 736-745 (1973).
Properties: Liquid. bp2.5 116-116.5°; bp 0.1 93-95°.
Boiling point: bp2.5 116-116.5°; bp 0.1 93-95°
 
Derivative Type: Methiodide
Molecular Formula: C12H20N2.2CH3I
Molecular Weight: 476.18
Percent Composition: C 35.31%, H 5.50%, N 5.88%, I 53.30%
Properties: Crystals, mp 239-240°.
Melting point: mp 239-240°
 
Use: To produce exptl parkinsonism: Everett et al., Science 124, 79 (1956).