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CAS No 51-43-4 , 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol

  • Name: 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
  • Synonyms: Adrenal; l-Adrenaline; adrenaline;4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol; L-epinephrine;Adrenalin; Levoepinephrine; Epipen; Hypernephrin; Epifrin;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 208-211 ºC
  • Density: 1.283 g/cm3
  • Refractive index: -51.5 ° (C=4, 1mol/L HCl)
  • Alpha: -51.5 º (C=4, 1M HCL, DRY SUB)
  • Water Solubility: <0.01 G/100 ML AT 18 ºC
  • Safety Statements: R23/24/25;R33;R36/37/38;R52/53
  • Hazard Symbols: T: Toxic;
  • EINECS: 200-098-7
  • Molecular Weight: 183.20442
  • InchiKey: UCTWMZQNUQWSLP-VIFPVBQESA-N
  • InChI: InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,
    1H3/t9-/m0/s1
  • Risk Statements: S23;S26;S36/37/39;S45;S61
  • Molecular Formula: C9H13NO3
  • Molecular Structure:CAS No:51-43-4 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
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51-43-4 epinephrine

  • Epinephrine(CAS bulk is 51-43-4) is administered, it is usually injected into the abounding across of the thigh, and not into a attitude, which could ahead it from animate appropriately. blast into the calmly or all-overs could could could cause a bl...
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51-43-4 L(-)-Epinephrine

  • Product Name: L(-)-Epinephrine Synonyms: (-)-epinephrine[qr];(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol;(r)-epinephrine[qr];1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (R)-;1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-,(R)...
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51-43-4 L(-)-Epinephrine

  • L(-)-Epinephrine English Synonyms: (-)-epinephrine[qr];(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol;(r)-epinephrine[qr];1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (R)-;1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-,(R)-;1-1-...
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51-43-4 L(-)-Epinephrine

  • Product Name: L(-)-Epinephrine Synonyms: (-)-epinephrine[qr];(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol;(r)-epinephrine[qr];1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (R)-;1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-,(R)...
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51-43-4 L(-)-Epinephrine

  • L(-)-Epinephrine English Synonyms: (-)-epinephrine[qr];(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol;(r)-epinephrine[qr];1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (R)-;1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-,(R)-;1-1-...
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51-43-4 L(-)-Epinephrine

  • English Synonyms: (-)-epinephrine[qr];(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol;(r)-epinephrine[qr];1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (R)-;1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-,(R)-;1-1-(3,4-dihydroxyphe...
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51-43-4 High Purity Corticosteroids L (-) -Epinephrine CAS: 51-43-4 From China

  • English Synonyms: (-)-epinephrine[qr];(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol;(r)-epinephrine[qr];1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (R)-;1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-,(R)-;1-1-(3,4-dihydroxyphe...
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  • 51-43-4 body Building Steroids Powders L-Epinephrine Hydrochloride,CAS NO.: 51-43-4

    • English Synonyms: (-)-epinephrine[qr];(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol;(r)-epinephrine[qr];1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (R)-;1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-,(R)-;1-1-(3,4-dihydroxyphe...
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  • 51-43-4 L(-)-Epinephrine CAS NO.: 51-43-4 roy@yccreate.com

    • L(-)-Epinephrine English Synonyms: (-)-epinephrine[qr];(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol;(r)-epinephrine[qr];1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (R)-;1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-,(R)-;1-1-...
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    51-43-4 L(-)-Epinephrine

    • L(-)-Epinephrine English Synonyms: (-)-epinephrine[qr];(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol;(r)-epinephrine[qr];1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (R)-;1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-,(R)-;1-1-...
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    References of 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
    Title: Epinephrine
    CAS Registry Number: 51-43-4
    CAS Name: 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
    Synonyms: (-)-3,4-dihydroxy-a-[(methylamino)methyl]benzyl alcohol; l-1-(3,4-dihydroxyphenyl)-2-(methylamino)ethanol; l-3,4-dihydroxy-1-[1-hydroxy-2-(methylamino)ethyl]benzene; l-methylaminoethanolcatechol; adrenaline; levorenin
    Trademarks: Anapen (Celltech); EpiPen (Dey); Primatene Mist (Wyeth); Sus-phrine (Forest)
    Molecular Formula: C9H13NO3
    Molecular Weight: 183.20
    Percent Composition: C 59.00%, H 7.15%, N 7.65%, O 26.20%
    Literature References: Endogenous catcholamine with combined a- and b-agonist activity. Principal sympathomimetic hormone produced by the adrenal medulla. Isoln from animal adrenal glands: Takamine, J. Soc. Chem. Ind. 20, 746 (1901); Aldrich, Am. J. Physiol. 5, 457 (1901). Synthesis of dl-form: Stolz, Ber. 37, 4149 (1904); Payne, Ind. Chem. 37, 523 (1961). Historic review of syntheses: Loewe, Arzneim.-Forsch. 4, 583 (1954). Resolution of dl-form: Fl?cher, Z. Physiol. Chem. 58, 189 (1908). Configuration: Pratesi et al., J. Chem. Soc. 1958, 2069. Acute toxicity: A. M. Lands et al., J. Pharmacol. Exp. Ther. 90, 110 (1947). HPLC determn in plasma and urine: C. R. Benedict, J. Chromatogr. 385, 369 (1987). Comprehensive description: D. H. Szulczewski, W.-H. Hong, Anal. Profiles Drug Subs. 7, 193-229 (1978). Physiologic review: Malmejac, Physiol. Rev. 44, 186 (1964). Review of biosynthesis: L. A. Pohorecky, R. J. Wurtman, Pharmacol. Rev. 23, 1-35 (1971); of pharmacology and clinical use in cardiopulmonary resuscitation: N. A. Paradis, E. M. Koscove, Ann. Emerg. Med. 19, 1288-1301 (1990); P. Hebert et al., J. Emerg. Med. 9, 487-495 (1991). Review of use in anaphylaxis: A. P. C. McLean-Tooke et al., Br. Med. J. 327, 1332-1335 (2003).
    Properties: Minute crystals, gradually browning on exposure to light and air. mp 211-212°. mp ~215° (dec) when rapidly heated. [a]D25 -50.0° to -53.5° (in 0.6N HCl). Very slightly sol in water, alc. Readily sol in aq solns of mineral acids, NaOH, and KOH. Insol in aq solns of ammonia and of the alkali carbonates. Insol in chloroform, ether, acetone, oils. LD50 i.p. in mice: 4 mg/kg (Lands).
    Melting point: mp 211-212°; mp ~215° (dec) when rapidly heated
    Optical Rotation: [a]D25 -50.0° to -53.5° (in 0.6N HCl)
    Toxicity data: LD50 i.p. in mice: 4 mg/kg (Lands)
     
    Derivative Type: Hydrochloride
    CAS Registry Number: 55-31-2
    Trademarks: Adrenalin (Monarch); Epifrin (Allergan); Glaucon (Alcon); Suprarenin (Aventis)
    Molecular Formula: C9H13NO3.HCl
    Molecular Weight: 219.67
    Percent Composition: C 49.21%, H 6.42%, N 6.38%, O 21.85%, Cl 16.14%
     
    Derivative Type: d-Bitartrate
    CAS Registry Number: 51-42-3
    Trademarks: Asthmahaler (Menley & James); Medihaler-Epi (3M Pharma)
    Molecular Formula: C9H13NO3.C4H6O6
    Molecular Weight: 333.29
    Percent Composition: C 46.85%, H 5.75%, N 4.20%, O 43.20%
    Properties: Crystals, mp 147-154° (some dec). Darkens slowly on exposure to air and light. One gram dissolves in about 3 ml water. Slightly sol in alc.
    Melting point: mp 147-154° (some dec)
     
    Derivative Type: dl-Form
    CAS Registry Number: 329-65-7
    Synonyms: Racepinephrine
    Properties: Sparingly sol in water, alcohol.
     
    Derivative Type: dl-Form hydrochloride
    CAS Registry Number: 329-63-5
    Trademarks: Vaponefrin (Novartis)
    Properties: Crystals from alcohol, mp 157°. Readily sol in water; sparingly sol in abs alc.
    Melting point: mp 157°
     
    Therap-Cat: Bronchodilator; cardiostimulant; mydriatic; antiglaucoma.
    Therap-Cat-Vet: Vasoconstrictor; cardiostimulant.
    Keywords: a-Adrenergic Agonist; ?Adrenergic Agonist; Antiglaucoma; Bronchodilator; Ephedrine Derivatives; Decongestant; Mydriatic.