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CAS No 51-21-8 , 5-fluoro-1H-pyrimidine-2,4-dione

  • Name: 5-fluoro-1H-pyrimidine-2,4-dione
  • Synonyms: 5-Fluorouracil; Carac; Fluoroplex; Adrucil; Fluracil; Efudex; 5-FU; Fluoroblastin; fluorouracil;5-fluoro-1H-pyrimidine-2,4-dione; 51-21-8;
  • CAS Registry Number:
  • Transport: UN 2811 6.1/PG 3
  • Melting Point: 278-286 ºC
  • Density: 1.53 g/cm3
  • Refractive index: 1.542
  • Water Solubility: 12.2 G/L 20 ºC
  • Safety Statements: R20/21/22
  • Hazard Symbols: Xn: Harmful;
  • HS Code: 29335995
  • EINECS: 200-085-6
  • Molecular Weight: 130.077223
  • InchiKey: GHASVSINZRGABV-UHFFFAOYSA-N
  • InChI: InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
  • Risk Statements: S36/37
  • Molecular Formula: C4H3FN2O2
  • Molecular Structure:CAS No:51-21-8 5-fluoro-1H-pyrimidine-2,4-dione
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51-21-8 5-FLUOROURACIL

  • 5-FLUOROURACIL
  • United States INTERNATIONAL LABORATORY LIMITED [Manufacturer]
  • Tel: ( 650 ) 278-9963
  • Fax: ( 650 ) 589-2786
  • Address: 1067 SNEATH LN SAN BRUNO CA 94066, USA SAN BRUNOUNITED STATES SAN BRUNO,nullUnited States
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51-21-8 5-Fluorouracil

  • 5-Fluorouracil
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
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51-21-8 5-Fluorouracil

  • 5-Fluorouracil
  • United States RIA International [Manufacturer]
  • Tel: 19735811282
  • Fax: 19735811283
  • Address: 11 Melanie Lane #17 East Hanover 07936 NJ UNITED STATES NJ,nullUnited States
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51-21-8 5-Fluorouracil

  • China BINHAI HANHONG BIOCHEMICAL CO., LTD. [Manufacturers]
  • Tel: +86-21-54302127
  • Fax: +86-21-54291107
  • Address: Room 209,Zonghe Building ,Jiachuan Road 245, Xuhui District, Shanghai, China Shanghai,ShanghaiChina
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51-21-8 FLUOROURACIL

  • FLUOROURACIL, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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51-21-8 5-Fluorouracil / Fluorouracilum

  • 5-Fluorouracil / Fluorouracilum
  • United States Ivy Fine Chemicals [Manufacturer]
  • Tel: 856-465-8550
  • Fax: 856-616-1161
  • Address: Ivy Fine Chemicals
    1312 Bunker Hill Drive
    Cherry Hill, NJ 08003
    USA null,nullUnited States
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51-21-8 5-Fluorouracil

  • China ORCHID CHEMICAL SUPPLIES LTD (OCS) [Importer/Exporter]
  • Tel: +86-571-85395792
  • Fax: +86-571-85420103
  • Address: 607, North Zhongshan Road, Hangzhou 310000 China null,ZhejiangChina
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51-21-8 5-Fluorouracil

  • 5-Fluorouracil
  • China Four Rivers Science Co., Ltd. [Manufacturer]
  • Tel: +86-28-86276120
  • Fax: +86-28-85193812
  • Address: A-704, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
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51-21-8 5-Fluorouracil

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China null,ZheJiangChina
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51-21-8 5-Fluorouracil

  • China Laiwu Hehui Chemical Co.,Ltd. null
  • Tel: +86-(531)-88772589
  • Fax: +86-(531)-88772589
  • Address: Huashan Rd., Jinan City, Shandong 250000, null,nullChina
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References of 5-fluoro-1H-pyrimidine-2,4-dione
Title: Fluorouracil
CAS Registry Number: 51-21-8
CAS Name: 5-Fluoro-2,4(1H,3H)-pyrimidinedione
Synonyms: 2,4-dioxo-5-fluoropyrimidine; 5-FU
Manufacturers' Codes: Ro-2-9757; NSC-19893
Trademarks: Adrucil (Adria); Arumel (SS Pharm.); Efudex (Roche); Efudix (Roche); Fluril; Fluracil; Fluoroplex (Allergan); Fluroblastin (Farmitalia); Fluro Uracil; Timazin (Torii)
Molecular Formula: C4H3FN2O2
Molecular Weight: 130.08
Percent Composition: C 36.93%, H 2.32%, F 14.61%, N 21.54%, O 24.60%
Literature References: Prepn: Duschinsky et al., J. Am. Chem. Soc. 79, 4559 (1957); Heidelberger, Duschinsky, US 2802005 (1957); US 2885396 (1959); Barton et al., J. Org. Chem. 37, 329 (1972); O. Miyashita et al., Chem. Pharm. Bull. 29, 3181 (1981). Pharmacokinetics: W. Sadee, C. G. Wong, Clin. Pharmacokinet. 2, 437 (1977). Site of action: F. Maley, G. F. Maley, FEBS Symp. 57, 21 (1979). Comprehensive description: B. C. Rudy, B. Z. Senkowski, Anal. Profiles Drug Subs. 2, 221-244 (1973); S. M. Bayomi, A. A. Al-Badr, ibid. 18, 599-639 (1989). Review of clinical trials: R. M. Hansen, Cancer Invest. 9, 637-642 (1991).
Properties: Crystals from water or methanol-ether, dec 282-283°. Sublimes (0.1 mm) 190-200°. uv max (0.1N HCl): 265-266 nm (e 7070).
Absorption maximum: uv max (0.1N HCl): 265-266 nm (e 7070)
 
Derivative Type: Sodium salt
Trademarks: Effluderm (Allergan)
 
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Pyrimidine Analogs.