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CAS No 5003-48-5 , (4-acetamidophenyl) 2-acetyloxybenzoate Search by region : China

  • Name: (4-acetamidophenyl) 2-acetyloxybenzoate
  • Synonyms: Fenasparate; Benoral;(4-acetamidophenyl) 2-acetyloxybenzoate; Salipran; Benorilatum [INN-Latin]; 5003-48-5;BENORYLATE; Benortan; Benorilato [Spanish];
  • CAS Registry Number:
  • Melting Point: 177-181 ºC
  • Flash Point: 279 ºC
  • Boiling Point: 537.8 ºC at 760 mmHg
  • Density: 1.286 g/cm3
  • Refractive index: 1.601
  • Safety Statements: Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by an unspecified route: respiratory stimulation, dehydration and distorted perceptions. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 279 ºC
  • EINECS: 225-674-5
  • Molecular Weight: 313.3047
  • InchiKey: FEJKLNWAOXSSNR-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H15NO5/c1-11(19)18-13-7-9-14(10-8-13)23-17(21)15-5-3-4-6-16
    (15)22-12(2)20/h3-10H,1-2H3,(H,18,19)
  • Molecular Formula: C17H15NO5
  • Molecular Structure:CAS No:5003-48-5 (4-acetamidophenyl) 2-acetyloxybenzoate

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References of (4-acetamidophenyl) 2-acetyloxybenzoate
Title: Benorylate
CAS Registry Number: 5003-48-5
CAS Name: 2-(Acetyloxy)benzoic acid 4-(acetylamino)phenyl ester
Synonyms: salicylic acid acetate, ester with 4-hydroxyacetanilide; 2-acetoxy-4￠-(acetamino)phenylbenzoate; p-acetamidophenyl acetylsalicylate; 4￠-(acetamido)phenyl-2-acetoxybenzoate; fenasprate
Manufacturers' Codes: Win-11450
Trademarks: Benoral (Sanofi Winthrop); Benortan (Sanofi Winthrop); Salipran (Evans)
Molecular Formula: C17H15NO5
Molecular Weight: 313.30
Percent Composition: C 65.17%, H 4.83%, N 4.47%, O 25.53%
Literature References: Prepn: NL 6504517 (1965 to Sterwin), C.A. 64, 8097c (1966), corresp to GB 1101747 (1968); Robertson, US 3431293 and Miller, GB 1168289 (both 1969 to Sterling Drug). Pharmacological investigations: Rosner et al., Therapie 23, 525 (1968); Raab, Arzneim.-Forsch. 21, 1662 (1971). Pharmacokinetic studies in animals: Liss, Palme, ibid. 19, 1177 (1969). Clinical evaluation: Bain, Burt, Clin. Trials J. 7, 307 (1970); Cardoe, ibid. 313.
Properties: Crystals from methanol or ethanol, mp 175-176°. LD50 in mice, rats (mg/ml): 2000, ~10000 orally; 1255, 1830 i.p. (Robertson).
Melting point: mp 175-176°
Toxicity data: LD50 in mice, rats (mg/ml): 2000, ~10000 orally; 1255, 1830 i.p. (Robertson)
Therap-Cat: Analgesic; anti-inflammatory; antipyretic.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Salicylic Acid Derivatives; Antipyretic.