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CAS No 50-19-1 , (2-hydroxy-2-phenylbutyl) carbamate

  • Name: (2-hydroxy-2-phenylbutyl) carbamate
  • Synonyms: AL-0361; Oxifenamatum; Listica; Oxifenamate; Phenylbutamate; Oxyphenamate;(2-hydroxy-2-phenylbutyl) carbamate;Oxyfenamate; Hidroxifenamato; Tensifen;
  • CAS Registry Number:
  • Flash Point: 205.1°C
  • Boiling Point: 415.4°C at 760 mmHg
  • Density: 1.18g/cm3
  • Refractive index: 1.545
  • Safety Statements: Moderately toxic by ingestion and intravenous routes. A minor tranquilizer. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES.
  • Flash Point: 205.1°C
  • EINECS: 200-017-5
  • Molecular Weight: 209.2417
  • InchiKey: WAFIYOULDIWAKR-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H15NO3/c1-2-11(14,8-15-10(12)13)9-6-4-3-5-7-9/h3-7,14H,2,
    8H2,1H3,(H2,12,13)
  • Molecular Formula: C11H15NO3
  • Molecular Structure:CAS No:50-19-1 (2-hydroxy-2-phenylbutyl) carbamate

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References of (2-hydroxy-2-phenylbutyl) carbamate
Title: Hydroxyphenamate
CAS Registry Number: 50-19-1
CAS Name: 2-Phenyl-1,2-butanediol 1-carbamate
Synonyms: carbamic acid b-ethyl-b-hydroxyphenethyl ester; b-ethyl-b-hydroxyphenethyl carbamic acid ester; b-ethyl-b-hydroxyphenethyl carbamate; 2-hydroxy-2-phenylbutyl carbamate
Manufacturers' Codes: AL-0361
Trademarks: Listica
Molecular Formula: C11H15NO3
Molecular Weight: 209.24
Percent Composition: C 63.14%, H 7.23%, N 6.69%, O 22.94%
Literature References: Prepd from b-ethyl-b-hydroxyphenethyl alcohol and ethyl chloroformate followed by reaction with ammonia: Sifferd, Braitberg, US 3066164 (1962 to Armour-Pharm.). Pharmacology and toxicology: Bastian, Clements, Dis. Nerv. Syst. 22, 9 (1961).
Properties: Crystals, mp 55-56.5°. Soly in water at 25°: 2.5% w/v. LD50 orally in mice: 830 mg/kg (Bastian, Clements).
Melting point: mp 55-56.5°
Toxicity data: LD50 orally in mice: 830 mg/kg (Bastian, Clements)
Therap-Cat: Anxiolytic.
Keywords: Anxiolytic; Carbamates.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.