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CAS No 486-47-5 , 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinoline

  • Name: 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinoline
  • Synonyms: Ethaverinum [INN-Latin]; Isovex; Barbonin;Ethylpapaverine; Dyscural; Barbonine; Ethaverine [INN];1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinoline; Etaverina [INN-Spanish];
  • CAS Registry Number:
  • Flash Point: 185.9°C
  • Boiling Point: 527.1°Cat760mmHg
  • Density: 1.104g/cm3
  • Refractive index: 1.565
  • Flash Point: 185.9°C
  • EINECS: 207-633-3
  • Molecular Weight: 395.49136
  • InchiKey: ZOWYFYXTIWQBEP-UHFFFAOYSA-N
  • InChI: InChI=1S/C24H29NO4/c1-5-26-21-10-9-17(14-22(21)27-6-2)13-20-19-16-24(29-
    8-4)23(28-7-3)15-18(19)11-12-25-20/h9-12,14-16H,5-8,13H2,1-4H3
  • Molecular Formula: C24H29NO4
  • Molecular Structure:CAS No:486-47-5 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinoline

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486-47-5 Ethaverine

  • Ethaverine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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486-47-5 Ethaverine

  • Ethaverine, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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486-47-5 ETHAVERINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinoline
Title: Ethaverine
CAS Registry Number: 486-47-5
CAS Name: 1-[(3,4-Diethoxyphenyl)methyl]-6,7-diethoxyisoquinoline
Synonyms: 6,7-diethoxy-1-(3,4-diethoxybenzyl)isoquinoline; ethylpapaverine
Trademarks: Dyscural
Molecular Formula: C24H29NO4
Molecular Weight: 395.49
Percent Composition: C 72.89%, H 7.39%, N 3.54%, O 16.18%
Literature References: Tetraethyl homolog of papaverine. Synthesis: Wolf, US 1962224 (1934).
Properties: Crystals from alcohol + ether, mp 99-101°. Insol in water. Readily sol in hot alc; slightly in ether and chloroform.
Melting point: mp 99-101°
 
Derivative Type: Hydrochloride
CAS Registry Number: 985-13-7
Trademarks: Barbonin (Knoll); Circubid (W. F. Merchant); Diquinol (Parke-Davis); Ethabid (Meyer); Isovex; Laverin (Lemmon); Perparin (Chemopuro); Perperine
Molecular Formula: C24H29NO4.HCl
Molecular Weight: 431.95
Percent Composition: C 66.73%, H 7.00%, N 3.24%, O 14.82%, Cl 8.21%
Literature References: Prepn of stable solns: Hereld, US 2971888 (1961).
Properties: Crystals from abs alc, mp 186-188° (dec). One gram dissolves in about 40 ml water. pH of 1% soln 3.6; of 0.1% soln 4.6.
Melting point: mp 186-188° (dec)
 
Derivative Type: Acid oxalate
Molecular Formula: C24H29NO4.(COOH)2
Molecular Weight: 485.53
Percent Composition: C 64.32%, H 6.44%, N 2.88%, O 26.36%
Properties: Crystals from alc, soluble in hot water.
 
Derivative Type: Salt with 7-iodo-8-hydroxyquinoline-5-sulfonic acid
Literature References: Prepn: HU 106906 (1931); v. Issekutz et al., Arch. Exp. Pathol. Pharmakol. 164, 158 (1932).
 
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic.