Home > Name List By c > Cinchonidine China

CAS No 485-71-2 , Cinchonidine Search by region : China

  • Name: Cinchonidine
  • Synonyms: alpha-Quinidine; 98%; L-Cinchonidine; alpha-Quinidine; (8alpha,9R)-Cinchonan-9-ol;4-Quinolyl-(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol;Cinchonidine;
  • CAS Registry Number:
  • Transport: 1544
  • Melting Point: 204-206 ºC
  • Density: 1.2 g/cm3
  • Refractive index: -107.5 ° (C=1, EtOH)
  • Alpha: -115 º (C=1, ETOH)
  • Safety Statements: R20/21/22
  • Hazard Symbols: Xn: Harmful;
  • HS Code: 29392900
  • EINECS: 207-622-3
  • Molecular Weight: 294.39
  • InChI: InChI=1/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2
  • Risk Statements: S36/37
  • Molecular Formula: C19H22N2O
  • Molecular Structure:CAS No:485-71-2 Cinchonidine

Related products

Select to

485-71-2 Cinchonidine;CAS No. 485-71-2

  • Cinchonidine;(R)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol CAS No. 485-71-2 Product Name: Cinchonidine Chemical Name: (R)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol Synonyms: (8-alpha,9r)-cin...
  • Min. Order: 22
  • China Shanghai Goyic Pharmaceutical &Chemical Co.,Ltd. [Manufacturer]
  • Tel: 86-21-50689757
  • Address: Building 19, No 528, Rui-Qing Road, PuDong New Area, Shanghai, China Shanghai,ShanghaiChina
Contact Supplier

485-71-2 Cinchonidine

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
Contact Supplier

485-71-2 Cinchonidine

  • China Fast Pharm Co.,Ltd [Manufacturers]
  • Tel: 8602133538380
  • Fax: 86-021-32082820
  • Address: No.17#-6D. 830 Lane,Maotai Road Shanghai,SH200336,China Shanghai,ShanghaiChina
Contact Supplier

485-71-2 Cinchonidine

  • CinchonidineCinchonidine, 98%
  • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-023-67030808-8010
  • Fax: +86-023-67030809
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,nullChina
Contact Supplier

485-71-2 Cinchonidine

  • Cinchonidine, 98%
  • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturer]
  • Tel: +86-21-64968086
  • Fax: +86-21-64968086
  • Address: Room 128, Building B, No. 8 Lane 1305, Huajing Road, Xuhui District, Shanghai, P.R. China 200000 Shanghai CHINA Shanghai,nullChina
Contact Supplier

485-71-2 Cinchonidine

  • China Shanghai Hanhong Chemical Co., Ltd. [Manufacturer, Trading Company, Agent]
  • Tel: +86-(21)-64762736, 64531573
  • Fax: +86-(21)-54291107
  • Address: 206-209, NO.1 Building , NO.245,Jiachuan Road, Xuhui District, Shanghai, Xuhui District,ShanghaiChina
Contact Supplier

485-71-2 Cinchonidine

  • China SHANGHAI HANHONG CHEMICAL CO.,LTD. [Manufacturers]
  • Tel: 021-64545202
  • Fax: 021-54291107
  • Address: Room 207, Zenghe Building , No.245, Jiachuan Road, Xuhui District, Shanghai, China shanghai,shanghaiChina
Contact Supplier

485-71-2 Cinchonidine

  • Cinchonidine
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
Contact Supplier

485-71-2 Cinchonidine

  • China BINHAI HANHONG BIOCHEMICAL CO., LTD. [Manufacturers]
  • Tel: +86-21-54302127
  • Fax: +86-21-54291107
  • Address: Room 209,Zonghe Building ,Jiachuan Road 245, Xuhui District, Shanghai, China Shanghai,ShanghaiChina
Contact Supplier

485-71-2 Cinchonidine

  • Cinchonidine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

Select to

1/2
1 2 Next
References of Cinchonidine
Title: Cinchonidine
CAS Registry Number: 485-71-2
CAS Name: (8a,9R)-Cinchonan-9-ol
Synonyms: cinchovatine; a-quinidine
Molecular Formula: C19H22N2O
Molecular Weight: 294.39
Percent Composition: C 77.52%, H 7.53%, N 9.52%, O 5.43%
Literature References: Occurs in most varieties of cinchona bark, especially in bark of Cinchona pubescens Vahl. (C. succirubra Pav.) and C. pitayensis Wedd., Rubiaceae. Isoln: Leers, Ann. 82, 147 (1852). Structure: Rabe, ibid. 365, 359 (1909). Stereoisomeric with cinchonine: Koenigs, ibid. 347, 182 (1906). Configuration: Prelog, Zalán, Helv. Chim. Acta 27, 535 (1944); Prelog, H?fliger, ibid. 33, 2021 (1950); Roth, Pharmazie 16, 257 (1961); Lyle, Keefer, Tetrahedron 23, 3253 (1967). Biosynthetic studies: Battersby, Parry, Chem. Commun. 1971, 31. Toxicity studies: C. C. Johnson, C. F. Poe, Acta Pharmacol. Toxicol. 4, 265 (1948); E. W. Schafer, Jr. et al., Ecotoxicol. Environ. Saf. 6, 149 (1982).
Properties: Orthorhombic plates, prisms from alcohol, mp 210°. [a]D20 -109.2° (alc). uv absorption data: Kamath et al., Indian J. Chem. 6, 510 (1968). Sol in alcohol and chloroform; moderately sol in ether. Practically insol in water. pK1 5.80, pK2 10.03. Protect from light. LD50 i.p. in rats: 206 mg/kg (Johnson, Poe). LD50 orally in quail: >316 mg/kg (Schafer).
Melting point: mp 210°
pKa: pK1 5.80, pK2 10.03
Optical Rotation: [a]D20 -109.2° (alc)
Toxicity data: LD50 i.p. in rats: 206 mg/kg (Johnson, Poe); LD50 orally in quail: >316 mg/kg (Schafer)
 
Derivative Type: Dihydrochloride
Molecular Formula: C19H22N2O.2HCl
Molecular Weight: 367.31
Percent Composition: C 62.13%, H 6.59%, N 7.63%, O 4.36%, Cl 19.30%
Properties: White or slightly yellow crystals or powder. Freely sol in water or alcohol. Protect from light.
 
Derivative Type: Hydrochloride dihydrate
Molecular Formula: C19H22N2O.HCl.2H2O
Molecular Weight: 366.88
Percent Composition: C 62.20%, H 7.42%, N 7.64%, O 13.08%, Cl 9.66%
Properties: Cryst powder; loses all of its H2O at 120°. [a]D20 -117.5° (water). Sol in 25 parts cold water, more sol in boiling water; sol in alcohol, chloroform, slightly in ether. The aq soln is practically neutral. Protect from light.
Optical Rotation: [a]D20 -117.5° (water)
 
Derivative Type: Sulfate trihydrate
Molecular Formula: (C19H22N2O)2.H2SO4.3H2O
Molecular Weight: 740.91
Percent Composition: C 61.60%, H 7.07%, N 7.56%, O 19.43%, S 4.33%
Properties: Silky, acicular crystals; efflorescent on exposure to air and darkens in light. mp when anhydr ~240° with decompn. One gram dissolves in 70 ml water, 20 ml hot water, 90 ml alcohol, 40 ml hot alc, 620 ml chloroform. Practically insol in ether. The aq soln is practically neutral. Protect from light.
Melting point: mp when anhydr ~240° with decompn
 
Derivative Type: Epicinchonidine
CAS Registry Number: 550-54-9
CAS Name: (8a,9S)-Cinchonan-9-ol
Properties: mp 104°, [a]D20 +63° (c = 0.804 in alc): Rabe et al., Ann. 492, 253 (1932).
Melting point: mp 104°
Optical Rotation: [a]D20 +63° (c = 0.804 in alc): Rabe et al., Ann. 492, 253 (1932)
 
Therap-Cat: Antimalarial.
Keywords: Antimalarial.