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CAS No 480-78-4 , platyphylline

  • Name: platyphylline
  • Synonyms: 12-Hydroxy-1,2-dihydrosenecionan-11,16-dione; BB 0262609;platyphylline; MolPort-006-111-401; ARONIS24349;Platifillin; SBB080770; SureCN1705886;
  • CAS Registry Number:
  • Transport: 1544
  • Density: 1.22 g/cm3
  • Refractive index: 1.553
  • Safety Statements: A poison by intraperitoneal and intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.
  • Hazard Symbols: Moderately toxic by ingestion.
  • EINECS: 207-558-6
  • Molecular Weight: 337.41068
  • InchiKey: BTHCJHQOYFUIMG-BQSAVQNUSA-N
  • InChI: InChI=1S/C18H27NO5/c1-4-12-9-11(2)18(3,
    22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4,11,13-15,22H,
    5-10H2,1-3H3/b12-4-/t11-,13+,14+,15+,18+/m0/s1
  • Molecular Formula: C18H27NO5
  • Molecular Structure:CAS No:480-78-4 platyphylline

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480-78-4 Platyphylline

  • Platyphylline, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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480-78-4 PLATYPHYLLINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of platyphylline
Title: Platyphylline
CAS Registry Number: 480-78-4
CAS Name: (1a)-1,2-Dihydro-12-hydroxysenecionan-11,16-dione
Synonyms: platifillin
Molecular Formula: C18H27NO5
Molecular Weight: 337.41
Percent Composition: C 64.07%, H 8.07%, N 4.15%, O 23.71%
Literature References: Toxic pyrrolizidine alkaloid from Senecio platyphyllus DC. and other Senecio spp., Compositae: Orékhov, Tiedebel, Ber. 68, 650 (1935); Orékhov et al., ibid. 1886; Konovalova, Orékhov, ibid. 69, 1908 (1936); Bull. Soc. Chim. Fr. [5] 4, 2037 (1937); Allen, Am. J. Pharm. 117, 110 (1945). Structure: Dry et al., J. Chem. Soc. 1955, 63. Comprehensive reviews of platyphylline and other pyrrolizidine alkaloids: L. Bull et al., The Pyrrolizidine Alkaloids (North-Holland, Amsterdam, 1968) 293 pp; F. L. Warren in The Alkaloids vol. 12, R. H. F. Manske, Ed. (Academic Press, New York, 1970) pp 245-331.
Properties: Crystals, mp 129°. [a]D20 -56.4° (c = 0.7 in chloroform). Practically insol in water. Sol in alcohol, chloroform, ether, dil acids.
Melting point: mp 129°
Optical Rotation: [a]D20 -56.4° (c = 0.7 in chloroform)
 
Derivative Type: Bitartrate
Molecular Formula: C18H27NO5.C4H6O6
Molecular Weight: 487.50
Percent Composition: C 54.20%, H 6.82%, N 2.87%, O 36.10%
Properties: Crystals, mp 199°. [a]D25 -40° (c = 2). Sol in 10 parts of water, in 5 parts of hot water. Sparingly sol in alc, in 42 parts of boiling alc. Nearly insol in chloroform, ether.
Melting point: mp 199°
Optical Rotation: [a]D25 -40° (c = 2)