Title: Leucocyanidin
CAS Registry Number: 480-17-1
CAS Name: 2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2
H-1-benzopyran-3,4,5,7-tetrol
Synonyms: 3,3¢,4,4¢,5,7-flavanhexol; 3,3¢,4,4¢,5,7-hexahydroxyflavane; leucocyanidol
Trademarks: Flavan (Pharmafarm); Hamaméliode P (Oberlin); Résivit (Oberlin)
Molecular Formula: C15H14O7
Molecular Weight: 306.27
Percent Composition: C 58.82%, H 4.61%, O 36.57%
Literature References: From petals of Asiatic cotton flowers (
Gossypium spp): Stephens,
Arch. Biochem. Biophys. 18, 449 (1948); from
Butea frondosa Koen. ex Roxb.,
Leguminosae: Ganguly, Seshadri,
Tetrahedron 6, 21 (1959). Prepn from quercetin: Bauer
et al., Chem. Ind. (London) 1954, 433; from taxifolin: Freudenberg, Weinges,
Ann. 613, 61 (1958). Metabolism: Claveau, Masquelier,
Can. J. Pharm. Sci. 1, 74 (1966).
See also Bioflavonoids.
Derivative Type: Monohydrate
Properties: Crystals from ethyl acetate + petr ether, mp above 355°. uv max (ethanol): 285 nm. Soluble in water, alcohol, acetone. Practically insol in ether, chloroform, petr ether.
Melting point: mp above 355°
Absorption maximum: uv max (ethanol): 285 nm
Therap-Cat: Capillary protectant.
Keywords: Vasoprotectant.