Title: Propyphenazone
CAS Registry Number: 479-92-5
CAS Name: 1,2-Dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3
H-pyrazol-3-one
Synonyms: 4-isopropylantipyrine; 4-isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one; 2,3-dimethyl-1-phenyl-4-isopropylpyrazolone; isopropylphenazone
Trademarks: Budirol (Fher); Causyth (Inverni); Eufibron (Berlin-Chemie); Isoprochin P (Merckle)
Molecular Formula: C14H18N2O
Molecular Weight: 230.31
Percent Composition: C 73.01%, H 7.88%, N 12.16%, O 6.95%
Literature References: Prepn: Stenz,
US 1972036 (1934 to Hoffmann-La Roche); Sawa,
J. Pharm. Soc. Jpn. 57, 953 (1937),
C.A. 32, 2533 (1938).
Properties: Slightly bitter crystals, mp 103°. Readily sol in alcohol, ether. Soly in water: 0.24 g/100 ml at 16.5°.
Melting point: mp 103°
Therap-Cat: Analgesic; antipyretic; anti-inflammatory.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Pyrazolones; Antipyretic.