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CAS No 46817-91-8 , 2-[(2-ethoxyphenoxy)methyl]morpholine

  • Name: 2-[(2-ethoxyphenoxy)methyl]morpholine
  • Synonyms: Emovit;2-[(2-ethoxyphenoxy)methyl]morpholine; 2-((2-ETHOXYPHENOXY)METHYL)MORPHOLINE; Viloxazina [INN-Spanish]; Viloxazinum [INN-Latin]; Viloxazin;
  • CAS Registry Number:
  • Melting Point: 185-186 ºC
  • Flash Point: 144.3 ºC
  • Boiling Point: 350.5 ºC at 760 mmHg
  • Density: 1.061 g/cm3
  • Refractive index: 1.499
  • Safety Statements: Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also VILOXAZINE HYDROCHLORIDE.
  • Flash Point: 144.3 ºC
  • EINECS: 256-281-7
  • Molecular Weight: 237.29486
  • InchiKey: YWPHCCPCQOJSGZ-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-
    6,11,14H,2,7-10H2,1H3
  • Molecular Formula: C13H19NO3
  • Molecular Structure:CAS No:46817-91-8 2-[(2-ethoxyphenoxy)methyl]morpholine

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46817-91-8 VILOXAZIN

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46817-91-8 Morpholine,2-[(2-ethoxyphenoxy)methyl]-

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46817-91-8 Morpholine,2-[(2-ethoxyphenoxy)methyl]-

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References of 2-[(2-ethoxyphenoxy)methyl]morpholine
Title: Viloxazine
CAS Registry Number: 46817-91-8
CAS Name: 2-[(2-Ethoxyphenoxy)methyl]morpholine
Synonyms: 2-(2-ethoxyphenoxymethyl)tetrahydro-1,4-oxazine
Manufacturers' Codes: ICI-58834
Molecular Formula: C13H19NO3
Molecular Weight: 237.29
Percent Composition: C 65.80%, H 8.07%, N 5.90%, O 20.23%
Literature References: Prepn: K. B. Mallion et al., GB 1138405; eidem, US 3714161 (1969, 1973 both to I.C.I.). Manufacturing process: S. A. Lee, GB 1260886; idem, US 3712890 (1972, 1973 both to I.C.I.). Pharmacology: Mallion et al., Nature 238, 157 (1972); Bereen, Lancet 1, 379 (1973). Toxicity: R. D. Brosnan et al., J. Int. Med. Res. 4, 83 (1976). Clinical evaluation in narcolepsy: C. Guilleminault et al., Sleep 9, 275 (1986). Review of pharmacology and therapeutic efficacy: R. M. Pinder et al., Drugs 13, 401 (1977).
 
Derivative Type: Hydrochloride
CAS Registry Number: 35604-67-2
Trademarks: Vivalan (Zeneca); Vicilan (Zeneca); Vivarint (Zeneca)
Molecular Formula: C13H19NO3.HCl
Molecular Weight: 273.76
Percent Composition: C 57.04%, H 7.36%, N 5.12%, O 17.53%, Cl 12.95%
Properties: mp 185-186°. LD50 in mice (mg/kg): 1000 orally, 60 i.v. (Brosnan).
Melting point: mp 185-186°
Toxicity data: LD50 in mice (mg/kg): 1000 orally, 60 i.v. (Brosnan)
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant.