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CAS No 457-60-3 , sodium

  • Name: sodium
  • Synonyms: Neoarsoluin; Miarsenol;Neosalvarsan; Collunovar; Novarsenol; NEOARSPHENAMINE; Novarsenobillon; Novarsenobenzol;sodium;[5-(3-amino-4-hydroxyphenyl)arsanylidenearsanyl-2-hydroxyanilino]
    methanesulfinate; Arsevan; Novarsenolum;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Safety Statements: Poison by intravenous and subcutaneous routes. When heated to decomposition it emits very toxic fumes of As, NOx, Na2O, and SOx. See also ARSENIC COMPOUNDS.
  • Hazard Symbols: Xn
  • Flash Point: °C
  • EINECS: 207-273-7
  • Molecular Weight: 466.151289
  • InchiKey: BGYSJUFVJUJSOL-UHFFFAOYSA-M
  • InChI: InChI=1S/C13H14As2N2O4S.Na/c16-10-5-8(1-3-12(10)18)14-15-9-2-4-13(19)11
    (6-9)17-7-22(20)21;/h1-6,17-19H,7,16H2,(H,20,21);/q;+1/p-1
  • Risk Statements: 22
  • Molecular Formula: C13H13As2N2NaO4S
  • Molecular Structure:CAS No:457-60-3 sodium

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References of sodium
Title: Neoarsphenamine
CAS Registry Number: 457-60-3
CAS Name: Sulfoxylic acid mono[[[5-[(3-amino-4-hydroxyphenyl)diarsenyl]-2-hydroxyphenyl]amino]methyl] ester monosodium salt
Synonyms: [5-[(3-amino-4-hydroxyphenyl)arseno]-2-hydroxyanilino]methanol sulfoxylate sodium; arsphenamine methylenesulfoxylic acid sodium salt; 3,3￠-diamino-4,4￠-dihydroxyarsenobenzenemethylenesulfoxylate sodium
Trademarks: Neosalvarsan (Hoechst); Collunovar; N.A.B.; Neo-Arsoluin; Vetarsenobillon; Novarsenobillon; Arsevan; Novarsan; Novarsenobenzol; Miarsenol
Molecular Formula: C13H13As2N2NaO4S
Molecular Weight: 466.15
Percent Composition: C 33.50%, H 2.81%, As 32.14%, N 6.01%, Na 4.93%, O 13.73%, S 6.88%
Literature References: Medicinal grade contains a small amount of inert inorganic salts and some solvent. The National Formulary requires 19+% As. Prepn from arsphenamine + sodium formaldehydesulfoxylate: Krumwiede, J. Am. Pharm. Assoc. 8, 795 (1919); Heyl, Miller, ibid. 11, 432 (1922); Dohr, US 1549465 (1925); Kober, US 1564859 (1926); Kraft et al., SU 158388 (1962). Physicochemical properties and toxicity: H. N. Wright et al., J. Pharmacol. Exp. Ther. 73, 12 (1941).
Properties: Yellow powder; odorless or slight odor. Oxidizes in air, becoming darker and more toxic; higher temps accelerate the oxidation; hence marketed in air-evacuated ampuls or filled with a nonoxidizing gas. Very sol in water; sol in glycerol. Slightly sol in alcohol or acetone. Practically insol in chloroform, ether. Its aq soln is practically neutral, unlike arsphenamine, which is acid.
Therap-Cat-Vet: Has been used in contagious pleuropneumonia, babesiasis, equine petechial fever, eperythrozoonosis.