Home > Name List By 4 > 4-hydroxy-3-[1-(4-hydroxy-2-oxochromen-3-yl)-2-methoxyethyl]chromen-2- one

CAS No 4366-18-1 , 4-hydroxy-3-[1-(4-hydroxy-2-oxochromen-3-yl)-2-methoxyethyl]chromen-2-
one

  • Name: 4-hydroxy-3-[1-(4-hydroxy-2-oxochromen-3-yl)-2-methoxyethyl]chromen-2-
    one
  • Synonyms: 3,3'-(2-methoxyethane-1,1-diyl)bis(2-hydroxy-4h-chromen-4-one); Cumetarolo;4-hydroxy-3-[1-(4-hydroxy-2-oxochromen-3-yl)-2-methoxyethyl]chromen-2-
    one;Cumetharol; Coumetarolum; 4366-18-1; Cumetarol;
  • CAS Registry Number:
  • Transport: 2811
  • Flash Point: 196°C
  • Boiling Point: 550.3°Cat760mmHg
  • Density: 1.514g/cm3
  • Refractive index: 1.693
  • Safety Statements:
    RIDADR 2811
    HazardClass 6.1(b)
    PackingGroup III
  • Flash Point: 196°C
  • EINECS: 224-455-1
  • Molecular Weight: 380.34754
  • InchiKey: BUCJFFQZPGTGPX-UHFFFAOYSA-N
  • InChI: InChI=1S/C21H16O7/c1-26-10-13(16-18(22)11-6-2-4-8-14(11)27-20(16)24)17-
    19(23)12-7-3-5-9-15(12)28-21(17)25/h2-9,13,22-23H,10H2,1H3
  • Molecular Formula: C21H16O7
  • Molecular Structure:CAS No:4366-18-1 4-hydroxy-3-[1-(4-hydroxy-2-oxochromen-3-yl)-2-methoxyethyl]chromen-2-<br />one

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References of 4-hydroxy-3-[1-(4-hydroxy-2-oxochromen-3-yl)-2-methoxyethyl]chromen-2-
one
Title: Coumetarol
CAS Registry Number: 4366-18-1
CAS Name: 3,3￠-(2-Methoxyethylidene)bis[4-hydroxy-2H-1-benzopyran-2-one]
Synonyms: 3,3￠-(2-methoxyethylidene)bis[4-hydroxycoumarin]; 1-methoxy-2,2-bis[4-hydroxy-3-coumarinyl]ethane; 4,4￠-dihydroxy-3,3￠-(2-methoxyethylidene)dicoumarin; 2,2-bis[4￠-hydroxy-3￠-coumarinyl]ethyl methyl ether; cumetharol; cumethoxaethane
Manufacturers' Codes: PH-137
Trademarks: Dicoumoxyl (Labaz); Dicumoxane (Boots)
Molecular Formula: C21H16O7
Molecular Weight: 380.35
Percent Composition: C 66.31%, H 4.24%, O 29.45%
Literature References: Prepn: Veldstra et al., Rec. Trav. Chim. 72, 358 (1953); GB 736388 and NL 80005 (both 1955 to N. V. Amsterdamsche Chininefabriek), C.A. 50, 10795a, 16874b (1956). Stereodynamics: Laruelle, Tetrahedron Lett. 1970, 2235. Has antivitamin K action. Activity studies: de Jongh, Kok, Arch. Int. Pharmacodyn. 94, 470 (1953); Gilgenkrantz et al., Ann. Med. Nancy 3, 115 (1964). Series of articles on clinical studies: Hutinel, Lyon Med. 23, 1569-1604 (1964).
Properties: Crystals from ethanol or methanol, mp 156-157°.
Melting point: mp 156-157°
Therap-Cat: Anticoagulant.
Keywords: Anticoagulant.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.