Home > Name List By 1 > 1-Propanamine,3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, N-oxide

CAS No 4317-14-0 , 1-Propanamine,3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, N-oxide

  • Name: 1-Propanamine,3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, N-oxide
  • Synonyms: Amitriptyline oxide;5H-Dibenzo[a,d]cycloheptene-D5,g-propylamine, 10,11-dihydro-N,N-dimethyl-, N-oxide(7CI,8CI);1-Propanamine,3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, N-oxide; Amitriptylinoxide;Equilibrin; Amitriptyline N-oxide;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Safety Statements: Poison by ingestion, intraperitoneal, and intravenous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: °C
  • Molecular Weight: 293.44
  • InChI: InChI=1/C20H23NO/c1-21(2,22)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3
  • Molecular Formula: C20H23 N O
  • Molecular Structure:CAS No:4317-14-0 1-Propanamine,3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, N-oxide

Related products

Search by region :

Select to

4317-14-0 AMITRIPTYLINE N OXIDE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
Contact Supplier

4317-14-0 AMITRIPTYLINE N OXIDE

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
Contact Supplier

Select to

1/1
References of 1-Propanamine,3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, N-oxide
Title: Amitriptylinoxide
CAS Registry Number: 4317-14-0
CAS Name: 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine N-oxide
Synonyms: 10,11-dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-D5,g-propylamine N-oxide; amitriptyline N-oxide
Trademarks: Ambivalon (Nattermann); Equilibrin (RPR)
Molecular Formula: C20H23NO
Molecular Weight: 293.40
Percent Composition: C 81.87%, H 7.90%, N 4.77%, O 5.45%
Literature References: Centrally acting metabolite of amitriptyline, q.v. Prepn: J. B. Pedersen, GB 991651; idem, US 3299139 (1965, 1967 both to Dumex). Series of articles on pharmacology, pharmacokinetics, metabolism, clinical studies, toxicity studies, teratological studies: Arzneim.-Forsch. 28, 1873-1926 (1978). HPLC determn: K. M. Jensen, J. Chromatogr. 183, 321 (1980). Neuropharmacology: J. Hyttel et al., Acta Pharmacol. Toxicol. 47, 53 (1980). Toxicity study: H. Friehe, R. Fontaine, Arzneim.-Forsch. 28, 1898 (1978).
Properties: Crystals, mp 228-230°. (Dihydrate, mp 102-103°.) LD50 in mice, guinea pigs, rabbits, dogs (mg/kg): between 330-460 orally; in mice, rats: 87, 25 i.v.; 320, 110 i.p. (Friehe, Fontaine).
Melting point: mp 228-230°; mp 102-103°
Toxicity data: LD50 in mice, guinea pigs, rabbits, dogs (mg/kg): between 330-460 orally; in mice, rats: 87, 25 i.v.; 320, 110 i.p. (Friehe, Fontaine).
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tricyclics.