Title: Fluprostenol
CAS Registry Number: 40666-16-8
CAS Name: (5
Z)-
rel-7-[(1
R,2
R,3
R,5
S)-3,5-Dihydroxy-2-[(1
E,3
R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic acid
Manufacturers' Codes: ICI-81008
Trademarks: Equimate
Molecular Formula: C23H29F3O6
Molecular Weight: 458.47
Percent Composition: C 60.25%, H 6.38%, F 12.43%, O 20.94%
Literature References: Potent luteolytic agent related to prostaglandin F2a,
q.v.: Dukes, Walpole,
Nature 250, 330 (1974). Prepn: Binder
et al., Prostaglandins 6, 87 (1974). Induction of estrus and luteolysis in mares: Cooper, Farr,
Vet. Rec. 94, 161 (1974); Berwyn-Jones, Irvine,
N. Z. Vet. J. 22, 107 (1974).
Derivative Type: Sodium salt
CAS Registry Number: 55028-71-2
Manufacturers' Codes: ICI-80008
Molecular Formula: C23H28F3NaO6
Molecular Weight: 480.45
Percent Composition: C 57.50%, H 5.87%, F 11.86%, Na 4.79%, O 19.98%
Therap-Cat-Vet: Treatment of infertility in mares.