Title: Fluroxene
CAS Registry Number: 406-90-6
CAS Name: (2,2,2-Trifluoroethoxy)ethene
Synonyms: 2,2,2-trifluoroethyl vinyl ether
Trademarks: Fluoromar (formerly) (Ohio Med.)
Molecular Formula: C4H5F3O
Molecular Weight: 126.08
Percent Composition: C 38.11%, H 4.00%, F 45.21%, O 12.69%
Line Formula: CF3CH2OCH=CH2
Literature References: First clinical fluorinated inhalation anesthetic agent. Prepd (not claimed): J. G. Shukys,
US 2830007; P. W. Townsend,
US 2870218 (1958, 1959 to Air Reduction). Anesthetic action: J. C. Krantz, Jr.
et al., J. Pharmacol. Exp. Ther. 108, 488 (1953). Review of metabolism and toxicity: V. Fiserova-Bergerova,
Environ. Health Perspect. 21, 225-230 (1977); L. S. Kaminsky, J. M. Fraser,
Crit. Rev. Toxicol. 19, 87-112 (1988).
Properties: Liquid. bp751 42.5°.
nD20 1.3192. d204 1.135.
Potentially explosive.
Boiling point: bp751 42.5°
Index of refraction: nD20 1.3192
Density: d204 1.135
CAUTION: Potential symptoms of overexposure are eye irritation; CNS depression, analgesia, anesthesia, seizures, respiratory depression.
See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 146.
Therap-Cat: Formerly as anesthetic (inhalation).