CAS No 395-28-8 , Benzenemethanol,4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-

Name: Benzenemethanol,4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-
Synonyms: 2-(3-Phenoxy-2-propylamino)-1-(p-hydroxyphenyl)-1-propanol;1-(p-Hydroxyphenyl)-2-(1-methyl-2-phenoxyethylamino)-1-propanol;Benzylalcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]- (6CI,8CI);Benzenemethanol,4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-;p-Hydroxy-N-(1-methyl-2-phenoxyethyl)norephedrine;p-Hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)-amino]ethyl]benzylalcohol;erythro-1-(p-Hydroxyphenyl)-2-(a-methyl-b-phenoxyethylamino)propanol;Isoxsuprine;
CAS Registry Number:395-28-8
Flash Point: 246.6°C
Boiling Point: 484.2°Cat760mmHg
Density: 1.146g/cm³
Safety Statements: Poison by ingestion, intravenous and intraperitoneal routes. A human teratogen. Human reproductive effects by ingestion: uterus, cervix and vagina effects. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x. Used to delay premature parturition (labor) and to accelerate fetal lung development.
Flash Point: 246.6°C
EINECS: 206-898-2
Molecular Weight: 301.42
InChI: InChI=1/C18H23NO3.ClH/c1-13(12-22-17-6-4-3-5-7-17)19-14(2)18(21)15-8-10-16(20)11-9-15;/h3-11,13-14,18-21H,12H2,1-2H3;1H/t13?,14?,18-;/m0./s1
Molecular Formula: C18H23 N O3
Molecular Structure:

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395-28-8 isoxsuprine

IUPAC NAME-4-{1-hydroxy-2-[(1-methyl-2-phenoxyethyl)amino]propyl}phenol MOLECULAR FORMULA-C18H23NO3 MOLAR MASS-301.38 g mol?1 Isoxsuprine is a drug used as a vasodilator in humans (under the trade name Duvadilan) and equines. Isoxsuprine is a beta-ad...
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References of Benzenemethanol,4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-

Title: Isoxsuprine
CAS Registry Number: 395-28-8
CAS Name: 4-Hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]benzenemethanol
Synonyms: p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]benzyl alcohol; p-hydroxy-N-(1-methyl-2-phenoxyethyl)norephedrine; 1-(p-hydroxyphenyl)-2-(1-methyl-2-phenoxyethylamino)-1-propanol; 2-(3-phenoxy-2-propylamino)-1-(p-hydroxyphenyl)-1-propanol
Molecular Formula: C18H23NO3
Molecular Weight: 301.38
Percent Composition: C 71.73%, H 7.69%, N 4.65%, O 15.93%
Literature References: Prepn: Moed, van Dijk, Rec. Trav. Chim. 75, 1215 (1956); GB 832286 and GB 832287 (both 1960 to N. V. Philip Gloeilampenfabrieken); Moed, US 3056836 (1962 to N. Am. Philips). Configuration: Dirkx, Rec. Trav. Chim. 83, 535 (1964). Toxicity data: Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971). Clinical evaluation in Raynaud's phenomenon: H. Wesseling et al., Eur. J. Clin. Pharmacol. 20, 329 (1981); in intermittent claudication: S. H. Skotnicki et al., Angiology 35, 685 (1984). Veterinary trial in navicular disease: A. S. Turner, C. M. Tucker, Equine Vet. J. 21, 338 (1989).
Properties: Crystals, mp 102.5-103.5°.
Melting point: mp 102.5-103.5°

Derivative Type: Hydrochloride
CAS Registry Number: 579-56-6
Trademarks: Dilavase (Organon); Duvadilan (Duphar); Duviculine (Duphar); Navilox (Univet); Suprilent (Duphar); Vadosilan (BMS); Vasodilan (BMS); Vasotran (BMS)
Molecular Formula: C18H23NO3.HCl
Molecular Weight: 337.84
Percent Composition: C 63.99%, H 7.16%, N 4.15%, O 14.21%, Cl 10.49%
Properties: Bitter crystals from water, mp 203-204°. Soly in water at 25° about 2.0% w/v; also sol in ethanol. LD50 in rats (mg/kg): 1750 orally; 164 i.p. (Goldenthal).
Melting point: mp 203-204°
Toxicity data: LD50 in rats (mg/kg): 1750 orally; 164 i.p. (Goldenthal)

Therap-Cat: Vasodilator (peripheral).
Therap-Cat-Vet: In treatment of navicular disease.
Keywords: Vasodilator (Peripheral).