Home > Name List By other > (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1, 4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2- ene-2-carbox...

CAS No 38821-53-3 , (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,
4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-
ene-2-carboxylic acid

  • Name: (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,
    4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-
    ene-2-carboxylic acid
  • Synonyms: Sefril;(6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,
    4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-
    ene-2-carboxylic acid; Cephradin; Anspor; Cefradina; 38821-53-3; Eskacef; Velosef; Cefradinum;Cefradine;
  • CAS Registry Number:
  • Melting Point: 140-142 C
  • Flash Point: 373°C
  • Boiling Point: 693.1°Cat760mmHg
  • Density: 1.47g/cm3
  • Refractive index: 1.684
  • Safety Statements: R36/37/38;R42/43
  • Hazard Symbols: Xi: Irritant;
  • Flash Point: 373°C
  • EINECS: 254-137-8
  • Molecular Weight: 349.40476
  • InchiKey: RDLPVSKMFDYCOR-UEKVPHQBSA-N
  • InChI: InChI=1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)
    10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,
    23)/t10-,11-,15-/m1/s1
  • Risk Statements: S26;S36
  • Molecular Formula: C16H19N3O4S
  • Molecular Structure:CAS No:38821-53-3 (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,<br />4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-<br />ene-2-carboxylic acid
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38821-53-3 Cefradine

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38821-53-3 Cefradine

  • China MOON CHEMICAL [Distributor/Wholesaler]
  • Tel: 86-574-27666863
  • Fax: 0574-27668686
  • Address: FLOOR 21,BUILDING 11,XINTIANDI,NO.689,SHIJIROAD,NINGBO, NINGBO,ZHEJIANGChina
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38821-53-3 Cefradine

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38821-53-3 Cefradine

  • China ruland chemistry co.,ltd. null
  • Tel: +86-025-86897711
  • Address: 1201,Heping Mansion,22 East Beijing Road,Nanjing,China. null,nullChina
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38821-53-3 Cefradine

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References of (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,
4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-
ene-2-carboxylic acid
Title: Cephradine
CAS Registry Number: 38821-53-3
CAS Name: (6R,7R)-7-[[(2R)-Amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms: 7-[D-2-amino-2-(1,4-cyclohexadienyl)acetamido]desacetoxycephalosporanic acid; cefradine
Manufacturers' Codes: SQ-11436
Trademarks: Cefro (Sankyo); Dexef (Dexo); Eskacef (GSK); Velocef (BMS); Zeefra (Bouchara-Recordati)
Molecular Formula: C16H19N3O4S
Molecular Weight: 349.40
Percent Composition: C 55.00%, H 5.48%, N 12.03%, O 18.32%, S 9.18%
Literature References: A semisynthetic cephalosporin antibiotic. Prepn and activity data: Weisenborn et al., US 3485819 (1969 to Squibb); Dolfini et al., J. Med. Chem. 14, 117 (1971). Clinical trials: Limson et al., Curr. Ther. Res. 14, 101 (1972); Landa, ibid. 496. Comprehensive description: K. Florey, Anal. Profiles Drug Subs. 5, 21-59 (1976). Review: W. E. Brown, J. R. Knill, in Pharmacological and Biochemical Properties of Drug Substances vol. 2, M. E. Goldberg, Ed. (Am. Pharm. Assoc., Washington, DC, 1979) pp 279-304.
 
Derivative Type: Monohydrate
CAS Registry Number: 75975-70-1
Properties: Small, colorless crystals. mp 140-142° (dec). pK1 2.63; pK2 7.27. Sol in propylene glycol; slightly sol in acetone, ethanol. Insol in ether, chloroform, benzene, hexane.
Melting point: mp 140-142° (dec)
pKa: pK1 2.63; pK2 7.27
 
Derivative Type: Dihydrate
CAS Registry Number: 31828-50-9
Manufacturers' Codes: SQ-22022
Properties: mp 183-185°.
Melting point: mp 183-185°
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Cephalosporins.