Home > Name List By other > (2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S, 5R,6R)-4-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-[(2R,3R,4S... China

CAS No 37339-90-5 , (2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,
5R,6R)-4-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-[(2R,3R,4S,5S,6R)-3,4,
5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,
5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-3,
5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,
5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5,
6-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol Search by region : China

  • Name: (2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,
    5R,6R)-4-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-[(2R,3R,4S,5S,6R)-3,4,
    5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,
    5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-3,
    5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,
    5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5,
    6-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
  • Synonyms: 37339-90-5;(2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,
    5R,6R)-4-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-[(2R,3R,4S,5S,6R)-3,4,
    5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,
    5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-3,
    5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,
    5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5,
    6-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol; A823605; AC1L1YB5;
  • CAS Registry Number:
  • Flash Point: 844°C
  • Boiling Point: 1472°Cat760mmHg
  • Density: 1.88g/cm3
  • Refractive index: 1.711
  • Safety Statements: Poison by intravenous route. An experimental teratogen. Experimental reproductive effects.
  • Flash Point: 844°C
  • Molecular Weight: 1152.99948
  • InchiKey: MAXBMUKIXLNXGX-DMWITZOWSA-N
  • InChI: InChI=1S/C42H72O36/c43-1-8-15(48)22(55)25(58)37(69-8)66-6-13-20(53)32(28
    (61)36(65)68-13)75-40-29(62)33(18(51)11(4-46)72-40)77-41-30(63)34(19(52)
    12(5-47)73-41)78-42-31(64)35(76-39-27(60)24(57)17(50)10(3-45)71-39)21
    (54)14(74-42)7-67-38-26(59)23(56)16(49)9(2-44)70-38/h8-65H,1-7H2/t8-,9-,
    10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22+,23+,24+,25-,26-,27-,
    28-,29-,30-,31-,32+,33+,34+,35+,36-,37-,38-,39+,40+,41+,42+/m1/s1
  • Molecular Formula: C42H72O36
  • Molecular Structure:CAS No:37339-90-5 (2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,<br />5R,6R)-4-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-[(2R,3R,4S,5S,6R)-3,4,<br />5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,<br />5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-3,<br />5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,<br />5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5,<br />6-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

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References of (2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,
5R,6R)-4-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-[(2R,3R,4S,5S,6R)-3,4,
5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,
5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-3,
5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,
5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5,
6-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
Title: Lentinan
CAS Registry Number: 37339-90-5
Manufacturers' Codes: LC-33
Literature References: (C6H10O5)n; mol wt 400,000-800,000. Neutral polysaccharide isolated from the edible mushroom, Lentinus edodes (Berk.) Sing. Primary structure is a b-1,3-D-glucan having 2 b-1,6-glucopyranoside branchings for every 5 b-1,3 linear linkages. Isoln and antitumor activity: G. Chihara et al., Nature 222, 637 (1969); eidem, Cancer Res. 30, 2776 (1970). Immunostimulant activity: Y. Y. Maeda, G. Chihara, Nature 229, 634 (1971). Prepn of stable aqueous solution: M. Fujii et al., NL 7601114; eidem, US 4207312 (1976, 1980 both to Ajinomoto; Morishita). Structural study: T. Sasaki et al., Carbohydr. Res. 47, 99 (1976). Preclinical evaluation and toxicity studies: G. Chihara, Adv. Exp. Med. Biol. 166, 189 (1983). Mechanism of action studies: H. Miyakoshi, T. Aoki, Int. J. Immunopharmacol. 6, 365, 373 (1984). Clinical trial in gastric and colorectal cancer: T. Taguchi et al., Adv. Exp. Med. Biol. 166, 181 (1983); K. Okuyama et al., Cancer 55, 2498 (1985). Review: G. Chihara, Int. J. Tissue Res. 4, 207-225 (1982).
Properties: White powder, dec 250°. Sol in aqueous alkali, formic acid. Slightly sol in hot water, DMSO. Insol in cold water, alcohol, ether, chloroform, pyridine, hexamethylphosphoramide. Stable against sulfuric and hydrochloric acids. [a]D20 +13.5-14.5° (in 2% NaOH); +19.5-21.5° (in 10% NaOH).
Optical Rotation: [a]D20 +13.5-14.5° (in 2% NaOH); +19.5-21.5° (in 10% NaOH)
Therap-Cat: Antineoplastic; immunomodulator.
Keywords: Antineoplastic; Immunomodulators; Immunomodulator.