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CAS No 370-14-9 , 4-[2-(methylamino)propyl]phenol

  • Name: 4-[2-(methylamino)propyl]phenol
  • Synonyms: Foledrin; Veritol; P-HYDROXYMETHAMPHETAMINE;Pulsotyl; Paredrinol; Pressitan; Sympropamin;4-[2-(methylamino)propyl]phenol; Isodrine; Isodrinum;
  • CAS Registry Number:
  • Flash Point: 109°C
  • Boiling Point: 279.4°Cat760mmHg
  • Density: 1.014g/cm3
  • Refractive index: 1.532
  • Safety Statements: Poison by subcutaneous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.
  • Hazard Symbols: Xi: Irritant;
  • Flash Point: 109°C
  • EINECS: 206-725-0
  • Molecular Weight: 165.2322
  • InchiKey: SBUQZKJEOOQSBV-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H15NO/c1-8(11-2)7-9-3-5-10(12)6-4-9/h3-6,8,11-12H,7H2,1-2H3
  • Risk Statements: 36/37/38
  • Molecular Formula: C10H15NO
  • Molecular Structure:CAS No:370-14-9 4-[2-(methylamino)propyl]phenol

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References of 4-[2-(methylamino)propyl]phenol
Title: Pholedrine
CAS Registry Number: 370-14-9
CAS Name: 4-[2-(Methylamino)propyl]phenol
Synonyms: p-hydroxy-N,a-dimethylphenethylamine; b-(p-hydroxyphenyl)isopropylmethylamine; a-(p-hydroxyphenyl)-b-methylaminopropane; p-hydroxy-N-methylbenzedrine
Manufacturers' Codes: Knoll H75
Molecular Formula: C10H15NO
Molecular Weight: 165.23
Percent Composition: C 72.69%, H 9.15%, N 8.48%, O 9.68%
Literature References: a-Adrenergic agonist. Prepd from p-methoxybenzyl methyl ketone: FR 822422, GB 482414, DE 674753 (1937, 1938 and 1939 to Knoll); Hildebrandt and Hildebrandt, Freese, DE 665793 and DE 767161 (1938 and 1951 to Knoll). Synthesis: Savitskii, Makhnenko, J. Gen. Chem. USSR 10, 1819 (1940); Buzas, Dufour, Bull. Soc. Chim. Fr. 1950, 139. Toxicity data: Lindner, Arch. Exp. Pathol. Pharmakol. 188, 675 (1938).
Properties: Crystals from methanol, mp 162-163°. Acrid, burning taste. Alkaline reactions. Slightly sol in water. Sol in alcohol, ether; readily sol in dil acids.
Melting point: mp 162-163°
 
Derivative Type: Sulfate
CAS Registry Number: 6114-26-7
Trademarks: Paredrinol (SK & F); Pulsotyl (Chinoin); Veritol (Knoll)
Molecular Formula: (C10H15NO)2.H2SO4
Molecular Weight: 428.54
Percent Composition: C 56.05%, H 7.53%, N 6.54%, O 22.40%, S 7.48%
Properties: Crystals, dec 320-323°. Sol in water. LD s.c. in rats: 500 mg/kg (Lindner).
Toxicity data: LD s.c. in rats: 500 mg/kg (Lindner)
 
Therap-Cat: Antihypotensive.
Therap-Cat-Vet: Circulatory stimulant.
Keywords: a-Adrenergic Agonist; Antihypotensive.