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CAS No 36590-19-9 , 1-Piperazinecarbothioamide,4-methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-

  • Name: 1-Piperazinecarbothioamide,4-methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-
  • Synonyms: 1-Piperazinecarbothioamide,4-methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-;CGP 6140;Amocarzine; S 80016; Phenthiourezine;
  • CAS Registry Number:
  • Flash Point: 276.5°C
  • Boiling Point: 533.6°Cat760mmHg
  • Density: 1.361g/cm3
  • Refractive index: 1.715
  • Flash Point: 276.5°C
  • Molecular Weight: 0
  • InChI: InChI=1/C18H21N5O2S/c1-21-10-12-22(13-11-21)18(26)20-16-4-2-14(3-5-16)19-15-6-8-17(9-7-15)23(24)25/h2-9,19H,10-13H2,1H3,(H,20,26)
  • Molecular Formula: C18H21 N5 O2 S
  • Molecular Structure:CAS No:36590-19-9 1-Piperazinecarbothioamide,4-methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-

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36590-19-9 Amocarzine

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  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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36590-19-9 1-Piperazinecarbothioamide,4-methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-

  • China Finechemie Co., Ltd. [Manufacturers]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone 400020 Chongqing CHINA Chongqing,ChongqingChina
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References of 1-Piperazinecarbothioamide,4-methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-
Title: Amocarzine
CAS Registry Number: 36590-19-9
CAS Name: 4-Methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-1-piperazinecarbothioamide
Synonyms: 4-nitro-4￠-[(N-methylpiperazinyl)thiocarbonylamino]diphenylamine
Manufacturers' Codes: CGP-6140
Molecular Formula: C18H21N5O2S
Molecular Weight: 371.46
Percent Composition: C 58.20%, H 5.70%, N 18.85%, O 8.61%, S 8.63%
Literature References: Orally active macrofilaricide; derivative of amoscanate, q.v. Prepn: BE 772053 (1971 to Agripat); R. Spaun et al., US 3781290 (1973 to Ciba-Geigy). Mechanism of action study: K. P. Davies et al., Exp. Parasitol. 68, 382 (1989). HPLC determn in biological fluids: S. C. Bhatia et al., J. Chromatogr. 434, 288 (1988). Pharmacokinetics: J. B. Lecaillon et al., Br. J. Clin. Pharmacol. 30, 625, 629 (1990). Clinical trial in onchocerciasis: A. A. Poltera et al., Lancet 337, 583 (1991).
Properties: mp 191-196°. Sol in acetonitrile.
Melting point: mp 191-196°
Therap-Cat: Anthelmintic (Nematodes).
Keywords: Anthelmintic (Nematodes).