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CAS No 364-98-7 , 7-chloro-3-methyl-4H-1λ Search by region : China

  • Name: 7-chloro-3-methyl-4H-1λ
  • Synonyms: Mutabase; Diazoxido; Hyperstat; Proglicem;Proglycem;6,2,4-benzothiadiazine 1,1-dioxide; Dizoxide; Hypertonalum; Diazossido; Eudemine;7-chloro-3-methyl-4H-1λ
  • CAS Registry Number:
  • Flash Point: 204.7°C
  • Boiling Point: 414.8°Cat760mmHg
  • Density: 1.61g/cm3
  • Refractive index: 1.691
  • Safety Statements: R22;R36/37/38
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 204.7°C
  • EINECS: 206-668-1
  • Molecular Weight: 230.67138
  • InchiKey: GDLBFKVLRPITMI-UHFFFAOYSA-N
  • InChI: InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,
    10,11)
  • Risk Statements: S22;S26;S36
  • Molecular Formula: C8H7ClN2O2S
  • Molecular Structure:CAS No:364-98-7 7-chloro-3-methyl-4H-1λ

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References of 7-chloro-3-methyl-4H-1λ
Title: Diazoxide
CAS Registry Number: 364-98-7
CAS Name: 7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
Synonyms: 3-methyl-7-chloro-1,2,4-benzothiadiazine 1,1-dioxide
Manufacturers' Codes: SRG-95213
Trademarks: Eudemine Injection (Schering); Proglicem (Essex); Hyperstat (Schering); Hypertonalum (Essex); Mutabase (Schering); Proglycem (Schering)
Molecular Formula: C8H7ClN2O2S
Molecular Weight: 230.67
Percent Composition: C 41.66%, H 3.06%, Cl 15.37%, N 12.14%, O 13.87%, S 13.90%
Literature References: Hypotensive agent that inhibits secretion of insulin from pancreatic beta cells. Prepn: A. A. Rubin et al., Science 133, 2067 (1961); J. G. Topliss et al., US 2986573; eidem, US 3345365 (1961, 1967 both to Schering); Raffa, Monzani, Farmaco Ed. Sci. 17, 244 (1962). Crystal and molecular structure: G. Bandoli, M. Nicolini, J. Cryst. Mol. Struct. 7, 229 (1978). Review of effect on insulin secretion: Nutr. Rev. 30, 194-198 (1972); of pharmacology and efficacy in hypertension: J. Koch-Weser, N. Engl. J. Med. 294, 1271-1274 (1976).
Properties: Crystals from dil alc, mp 330-331°. uv max (methanol): 268 nm (e 11300). Sol in alcohol and alkaline solns. Insol in water.
Melting point: mp 330-331°
Absorption maximum: uv max (methanol): 268 nm (e 11300)
Therap-Cat: Antihypoglycemic; antihypertensive.
Keywords: Antihypertensive; Thiazides and Analogs; Antihypoglycemic.