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CAS No 362-74-3 , Bucladesine Search by region : China

  • Name: Bucladesine
  • Synonyms: N-6,O-2'-Dibutyryl adenosine cyclic 3':5'-monophosphate; N-(9-beta-D-Ribofuranosyl-9H-furin-6-yl)-butyramide cyclic 3',5'-(hydrogen phosphate) 2'-butyrate;Bucladesine;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.72g/cm3
  • Refractive index: 1.717
  • Safety Statements: Human mutation data reported. When heated to decomposition it emits toxic fumes of POx and NOx. See also AMIDES.
  • Flash Point: °C
  • EINECS: 206-649-8
  • Molecular Weight: 469.39
  • InChI: InChI=1/C18H24N5O8P/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24)/t10-,14-,15-,18?/m1/s1
  • Molecular Formula: C18H24N5O8P
  • Molecular Structure:CAS No:362-74-3 Bucladesine

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References of Bucladesine
Title: Bucladesine
CAS Registry Number: 362-74-3
CAS Name: N-(1-Oxobutyl)adenosine cyclic 3￠,5￠-(hydrogen phosphate) 2￠-butanoate
Synonyms: N-(9-b-D-ribofuranosyl-9H-purin-6-yl)butyramide cyclic 3￠,5￠-(hydrogen phosphate) 2￠-butyrate; N6,2￠-O-dibutyryladenosine 3￠,5￠-cyclic monophosphate; N6,2￠-O-dibutyryl cAMP; DBcAMP
Molecular Formula: C18H24N5O8P
Molecular Weight: 469.39
Percent Composition: C 46.06%, H 5.15%, N 14.92%, O 27.27%, P 6.60%
Literature References: Vasodilating cyclic nucleotide derivative which can permeate the cell membrane. Mimics the action of endogenous cyclic AMP, q.v. Prepn: Th. Posternak et al., Biochim. Biophys. Acta 65, 558 (1962); O. Nagase et al., JP Kokai 76 113896, C.A. 86, 140409r (1977); T. Hirayama et al., JP Kokai 77 39698; JP 77 39699, C.A. 87, 136330m-136331n (1977) (1976, 1977, 1977 all to Daiichi Seiyaku). Pharmacology: H. S. White et al., Eur. J. Pharmacol. 57, 107 (1979); J. D. Johnson et al., ibid. 91, 343 (1983); N. Bondar et al., J. Physiol. 355, 33 (1984). Clinical trial in congestive heart failure: S. Matsui et al., Am. J. Cardiol. 51, 1364 (1983); after cardiopulmonary bypass surgery: T. Yoshitake et al., Prog. Clin. Biol. Res. 111, 211 (1983).
 
Derivative Type: Sodium salt
CAS Registry Number: 16980-89-5
Manufacturers' Codes: DC-2797
Trademarks: Actosin (Daiichi Seiyaku)
Molecular Formula: C18H23N5NaO8P
Molecular Weight: 491.37
Percent Composition: C 44.00%, H 4.72%, N 14.25%, Na 4.68%, O 26.05%, P 6.30%
 
Derivative Type: Barium salt
CAS Registry Number: 18837-96-2
Molecular Formula: C36H46BaN10O16P2
Molecular Weight: 1074.08
Percent Composition: C 40.26%, H 4.32%, Ba 12.79%, N 13.04%, O 23.83%, P 5.77%
Properties: uv max (ethanol-0.5M ammonium acetate, 5:2) 270 nm.
Absorption maximum: uv max (ethanol-0.5M ammonium acetate, 5:2) 270 nm
 
Therap-Cat: Cardiotonic.
Keywords: Cardiotonic.