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CAS No 3611-72-1 , 1-benzofuran-2-yl-(4-chlorophenyl)methanol

  • Name: 1-benzofuran-2-yl-(4-chlorophenyl)methanol
  • Synonyms: Cloridarol; Cloridarolum; Cloridarol (INN); Cloridarolum [INN-Latin];1-benzofuran-2-yl-(4-chlorophenyl)methanol; AC1L2FLM; Menacor; Menoxicor; 3611-72-1;Clobenfurol;
  • CAS Registry Number:
  • Flash Point: 202.1°C
  • Boiling Point: 410.5°Cat760mmHg
  • Density: 1.32g/cm3
  • Refractive index: 1.657
  • Flash Point: 202.1°C
  • EINECS: 222-780-3
  • Molecular Weight: 258.69964
  • InchiKey: KBFBRIPYVVGWRS-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H11ClO2/c16-12-7-5-10(6-8-12)15(17)14-9-11-3-1-2-4-13(11)18-
    14/h1-9,15,17H
  • Molecular Formula: C15H11ClO2
  • Molecular Structure:CAS No:3611-72-1 1-benzofuran-2-yl-(4-chlorophenyl)methanol

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3611-72-1 Cloridarol

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References of 1-benzofuran-2-yl-(4-chlorophenyl)methanol
Title: Clobenfurol
CAS Registry Number: 3611-72-1
CAS Name: a-(4-Chlorophenyl)-2-benzofuranmethanol
Synonyms: 2-benzofuryl-p-chlorophenylcarbinol
Trademarks: Menacor (Menarini)
Molecular Formula: C15H11ClO2
Molecular Weight: 258.70
Percent Composition: C 69.64%, H 4.29%, Cl 13.70%, O 12.37%
Literature References: Prepn: BE 644176; Ghelardoni, Russo, GB 1160925 (1964, 1969 both to Menarini), C.A. 63, 8319h (1965); 71, 124212f (1969); Ghelardoni, Russo, Boll. Chim. Farm. 109, 48 (1970). Pharmacology of the hemisuccinate deriv: Pisanti, Volterra, Farmaco Ed. Sci. 26, 312 (1971).
Properties: White, odorless powder, mp 48-49°.
Melting point: mp 48-49°
 
Derivative Type: Hemisuccinate
Molecular Formula: C19H15ClO5
Molecular Weight: 358.77
Percent Composition: C 63.61%, H 4.21%, Cl 9.88%, O 22.30%
Properties: mp 95-97° from petr ether. LD50 in mice, rats (mg/kg): 321, 300 i.p. (Pisanti, Volterra).
Melting point: mp 95-97° from petr ether
Toxicity data: LD50 in mice, rats (mg/kg): 321, 300 i.p. (Pisanti, Volterra)
 
Therap-Cat: Vasodilator (coronary).
Keywords: Vasodilator (Coronary).