Home > Name List By 2 > 2, 2-dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl] acetamide

CAS No 3576-64-5 , 2,
2-dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]
acetamide

  • Name: 2,
    2-dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]
    acetamide
  • Synonyms: Chlorphenoxamide; 3576-64-5; Clefamida [INN-Spanish]; Mebinol;2,
    2-dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]
    acetamide; EINECS 222-694-6; Moebinol; Clefamidum [INN-Latin];Chlorophenoxamide;
  • CAS Registry Number:
  • Flash Point: 286.6°C
  • Boiling Point: 550.3°Cat760mmHg
  • Density: 1.429g/cm3
  • Refractive index: 1.616
  • Flash Point: 286.6°C
  • EINECS: 222-694-6
  • Molecular Weight: 399.22534
  • InchiKey: ODCUSWJXZDHLKV-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H16Cl2N2O5/c18-16(19)17(23)20(9-10-22)11-12-1-5-14(6-2-12)
    26-15-7-3-13(4-8-15)21(24)25/h1-8,16,22H,9-11H2
  • Molecular Formula: C17H16Cl2N2O5
  • Molecular Structure:CAS No:3576-64-5 2,<br />2-dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]<br />acetamide

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References of 2,
2-dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]
acetamide
Title: Chlorphenoxamide
CAS Registry Number: 3576-64-5
CAS Name: 2,2-Dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]acetamide
Synonyms: N-(b-hydroxyethyl)-N-[p-(4-nitrophenoxy)benzyl]dichloroacetamide; N-(b-hydroxyethyl)-N-[p-phenoxy-(4￠-nitro)benzyl]dichloroacetamide; dichloro-N-(b-hydroxyethyl)-N-[p-(4￠-nitrophenoxy)benzyl]acetamide; clefamide; chlorophenoxamide
Trademarks: Mebinol (Erba)
Molecular Formula: C17H16Cl2N2O5
Molecular Weight: 399.23
Percent Composition: C 51.14%, H 4.04%, Cl 17.76%, N 7.02%, O 20.04%
Literature References: Prepn: Logemann et al., Farmaco Ed. Sci. 13, 139 (1958); US 2824894 (1958 to Carlo Erba). Antiamebic activity and toxicity data: Carneri, G. Mal. Infett. Parassit. 10, 850 (1958), C.A. 53, 5519C (1959).
Properties: Crystals from 95% ethanol, mp 136-137°. Practically insol in water (soly ~3 g/ml). Sol in ethanol, acetone, dioxane. LD50 in mice (mg/kg): >5000 orally, 2000 i.p. (Carneri).
Melting point: mp 136-137°
Toxicity data: LD50 in mice (mg/kg): >5000 orally, 2000 i.p. (Carneri)
NOTE: Do not confuse with chlorphenoxamine.
Therap-Cat: Antiamebic.
Keywords: Antiamebic.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.